Phenolic Compounds Known to Be Present in Lingonberry (<i>Vaccinium vitis-idaea</i> L.) Enhance Macrophage Polarization towards the Anti-Inflammatory M2 Phenotype

Phenolic Compounds Known to Be Present in Lingonberry (<i>Vaccinium vitis-idaea</i> L.) Enhance Macrophage Polarization towards the Anti-Inflammatory M2 Phenotype

Macrophages are pleiotropic immune cells whose phenotype can polarize towards the pro-inflammatory M1 or anti-inflammatory M2 direction as a response to environmental changes. In obesity, the number of macrophages in adipose tissue is enhanced, and they shift towards the M1 phenotype. Activated M1 m...

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Bibliographic Details
Main Authors: Riitta Ryyti, Mari Hämäläinen, Tiina Leppänen, Rainer Peltola, Eeva Moilanen
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Biomedicines
Subjects:
macrophage polarization
low-grade inflammation
obesity
lingonberry
polyphenol
resveratrol
Online Access:https://www.mdpi.com/2227-9059/10/12/3045

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