Structural and mutational analysis of MazE6-operator DNA complex provide insights into autoregulation of toxin-antitoxin systems
The dimeric MazE6 antitoxin binds to a specific sequence in its cognate operator DNA for autoregulation, and the key residues for dimerization and DNA binding are identified.
Main Authors: | Khushboo Kumari, Siddhartha P. Sarma |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-022-03933-5 |
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