Crystal structure of an HIV assembly and maturation switch

Crystal structure of an HIV assembly and maturation switch

Virus assembly and maturation proceed through the programmed operation of molecular switches, which trigger both local and global structural rearrangements to produce infectious particles. HIV-1 contains an assembly and maturation switch that spans the C-terminal domain (CTD) of the capsid (CA) regi...

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Bibliographic Details
Main Authors: Jonathan M Wagner, Kaneil K Zadrozny, Jakub Chrustowicz, Michael D Purdy, Mark Yeager, Barbie K Ganser-Pornillos, Owen Pornillos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-07-01
Series:eLife
Subjects:
HIV
capsid
assembly
Online Access:https://elifesciences.org/articles/17063

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