Industrial Biotechnology Based on Enzymes From Extreme Environments
Biocatalysis is crucial for a green, sustainable, biobased economy, and this has driven major advances in biotechnology and biocatalysis over the past 2 decades. There are numerous benefits to biocatalysis, including increased selectivity and specificity, reduced operating costs and lower toxicity,...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Bioengineering and Biotechnology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2022.870083/full |
| _version_ | 1811290379177164800 |
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| author | Noha M. Mesbah |
| author_facet | Noha M. Mesbah |
| author_sort | Noha M. Mesbah |
| collection | DOAJ |
| description | Biocatalysis is crucial for a green, sustainable, biobased economy, and this has driven major advances in biotechnology and biocatalysis over the past 2 decades. There are numerous benefits to biocatalysis, including increased selectivity and specificity, reduced operating costs and lower toxicity, all of which result in lower environmental impact of industrial processes. Most enzymes available commercially are active and stable under a narrow range of conditions, and quickly lose activity at extremes of ion concentration, temperature, pH, pressure, and solvent concentrations. Extremophilic microorganisms thrive under extreme conditions and produce robust enzymes with higher activity and stability under unconventional circumstances. The number of extremophilic enzymes, or extremozymes, currently available are insufficient to meet growing industrial demand. This is in part due to difficulty in cultivation of extremophiles in a laboratory setting. This review will present an overview of extremozymes and their biotechnological applications. Culture-independent and genomic-based methods for study of extremozymes will be presented. |
| first_indexed | 2024-04-13T04:11:50Z |
| format | Article |
| id | doaj.art-10707633bd724ed199c67441ee004107 |
| institution | Directory Open Access Journal |
| issn | 2296-4185 |
| language | English |
| last_indexed | 2024-04-13T04:11:50Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Bioengineering and Biotechnology |
| spelling | doaj.art-10707633bd724ed199c67441ee0041072022-12-22T03:03:05ZengFrontiers Media S.A.Frontiers in Bioengineering and Biotechnology2296-41852022-04-011010.3389/fbioe.2022.870083870083Industrial Biotechnology Based on Enzymes From Extreme EnvironmentsNoha M. MesbahBiocatalysis is crucial for a green, sustainable, biobased economy, and this has driven major advances in biotechnology and biocatalysis over the past 2 decades. There are numerous benefits to biocatalysis, including increased selectivity and specificity, reduced operating costs and lower toxicity, all of which result in lower environmental impact of industrial processes. Most enzymes available commercially are active and stable under a narrow range of conditions, and quickly lose activity at extremes of ion concentration, temperature, pH, pressure, and solvent concentrations. Extremophilic microorganisms thrive under extreme conditions and produce robust enzymes with higher activity and stability under unconventional circumstances. The number of extremophilic enzymes, or extremozymes, currently available are insufficient to meet growing industrial demand. This is in part due to difficulty in cultivation of extremophiles in a laboratory setting. This review will present an overview of extremozymes and their biotechnological applications. Culture-independent and genomic-based methods for study of extremozymes will be presented.https://www.frontiersin.org/articles/10.3389/fbioe.2022.870083/fullextremozymeextreme environmentsingle amplified genomemetagenomicshalophilealkaliphile |
| spellingShingle | Noha M. Mesbah Industrial Biotechnology Based on Enzymes From Extreme Environments Frontiers in Bioengineering and Biotechnology extremozyme extreme environment single amplified genome metagenomics halophile alkaliphile |
| title | Industrial Biotechnology Based on Enzymes From Extreme Environments |
| title_full | Industrial Biotechnology Based on Enzymes From Extreme Environments |
| title_fullStr | Industrial Biotechnology Based on Enzymes From Extreme Environments |
| title_full_unstemmed | Industrial Biotechnology Based on Enzymes From Extreme Environments |
| title_short | Industrial Biotechnology Based on Enzymes From Extreme Environments |
| title_sort | industrial biotechnology based on enzymes from extreme environments |
| topic | extremozyme extreme environment single amplified genome metagenomics halophile alkaliphile |
| url | https://www.frontiersin.org/articles/10.3389/fbioe.2022.870083/full |
| work_keys_str_mv | AT nohammesbah industrialbiotechnologybasedonenzymesfromextremeenvironments |