An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern
Deriphyllin has been a mainstay of asthma therapy despite its narrow therapeutic index and a large pharmacokinetic variability between patients. Here, the authors decided to report a rare case of suspected deriphyllin-induced hallucinations in adults for the first time. An 83-year-old male patient w...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2019-01-01
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| Series: | Apollo Medicine |
| Subjects: | |
| Online Access: | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=4;spage=247;epage=249;aulast=Dahiya |
| _version_ | 1819140084430012416 |
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| author | Mohit Dahiya Nehal R Parikh Deepak S Malhotra Shikha V Sood |
| author_facet | Mohit Dahiya Nehal R Parikh Deepak S Malhotra Shikha V Sood |
| author_sort | Mohit Dahiya |
| collection | DOAJ |
| description | Deriphyllin has been a mainstay of asthma therapy despite its narrow therapeutic index and a large pharmacokinetic variability between patients. Here, the authors decided to report a rare case of suspected deriphyllin-induced hallucinations in adults for the first time. An 83-year-old male patient who was a known case of recent onset asthma was on tablet deriphyllin 150 mg BD and salbutamol nebulization BD. He underwent emergency drainage of subdural hematoma due to a history of fall 20 days back with head injury. Within 2 days, he improved and was discharged 3 days later with the medicines. On follow-up after 7 days, he was admitted with a chief complaint of hallucinations. After stopping tablet deriphyllin, the patient's condition drastically improved in next few days and neurology was completely normal. Drug dechallenge was positive in this case since the hallucinations subsided after discontinuation of suspected drug deriphyllin. There are no such cases published previously. |
| first_indexed | 2024-12-22T11:32:56Z |
| format | Article |
| id | doaj.art-10738f0b45c84601b8e9d4dcfc6aeb27 |
| institution | Directory Open Access Journal |
| issn | 0976-0016 2213-3682 |
| language | English |
| last_indexed | 2024-12-22T11:32:56Z |
| publishDate | 2019-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Apollo Medicine |
| spelling | doaj.art-10738f0b45c84601b8e9d4dcfc6aeb272022-12-21T18:27:33ZengWolters Kluwer Medknow PublicationsApollo Medicine0976-00162213-36822019-01-0116424724910.4103/am.am_52_19An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concernMohit DahiyaNehal R ParikhDeepak S MalhotraShikha V SoodDeriphyllin has been a mainstay of asthma therapy despite its narrow therapeutic index and a large pharmacokinetic variability between patients. Here, the authors decided to report a rare case of suspected deriphyllin-induced hallucinations in adults for the first time. An 83-year-old male patient who was a known case of recent onset asthma was on tablet deriphyllin 150 mg BD and salbutamol nebulization BD. He underwent emergency drainage of subdural hematoma due to a history of fall 20 days back with head injury. Within 2 days, he improved and was discharged 3 days later with the medicines. On follow-up after 7 days, he was admitted with a chief complaint of hallucinations. After stopping tablet deriphyllin, the patient's condition drastically improved in next few days and neurology was completely normal. Drug dechallenge was positive in this case since the hallucinations subsided after discontinuation of suspected drug deriphyllin. There are no such cases published previously.http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=4;spage=247;epage=249;aulast=Dahiyaderiphyllindrug dechallengeelderlyvisual hallucinations |
| spellingShingle | Mohit Dahiya Nehal R Parikh Deepak S Malhotra Shikha V Sood An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern Apollo Medicine deriphyllin drug dechallenge elderly visual hallucinations |
| title | An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern |
| title_full | An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern |
| title_fullStr | An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern |
| title_full_unstemmed | An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern |
| title_short | An unusual occurrence of deriphyllin-induced hallucinations: Contingency of concern |
| title_sort | unusual occurrence of deriphyllin induced hallucinations contingency of concern |
| topic | deriphyllin drug dechallenge elderly visual hallucinations |
| url | http://www.apollomedicine.org/article.asp?issn=0976-0016;year=2019;volume=16;issue=4;spage=247;epage=249;aulast=Dahiya |
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