Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006
Background Polycystic ovarian syndrome (PCOS) was first introduced by Leventhal and Stein in 1935. It has a wide range of manifestations such as hyperandrogenism, irregular menstruation and central body obesity. The lack of definite diagnostic criteria has made the diagnosis a difficult task. Moreov...
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| Format: | Article |
| Language: | English |
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Royan Institute (ACECR), Tehran
2010-10-01
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| Series: | International Journal of Fertility and Sterility |
| Online Access: | http://www.ijfs.ir/article_45808_47edddbf4265f8bc11b871ecbae09747.pdf |
| _version_ | 1819008448644251648 |
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| author | Saghar Salehpour Hamidreza Esmaeilnia Shirvani Abbas Entezari |
| author_facet | Saghar Salehpour Hamidreza Esmaeilnia Shirvani Abbas Entezari |
| author_sort | Saghar Salehpour |
| collection | DOAJ |
| description | Background Polycystic ovarian syndrome (PCOS) was first introduced by Leventhal and Stein in 1935. It has a wide range of manifestations such as hyperandrogenism, irregular menstruation and central body obesity. The lack of definite diagnostic criteria has made the diagnosis a difficult task. Moreover, the disturbing aspects of the syndrome range from hirsutism in an adolescent girl to infertility in a young woman. Based on the Rotterdam 2003 Criteria, current diagnostic criteria must include two of the following three symptoms: 1. Either oligo-ovulation or anovulation, 2. Clinical or laboratory manifestations of hyperandrogenism, 3. Polycystic ovaries on sonographic examination (more than 12 follicles of less than 10 mm in diameter in each ovary). In this study, we have focused on the enrollment of a large sample size to assess the prevalence and clinical features of PCOS such that a wide range of basic information can be utilized for further investigations. Materials and methods This was a cross-sectional study with multi-stage random sampling. Subjects were selected from 15-18 years old girls from a number of high schools in Tehran. After interview and clinical examination, those individuals with either menstrual irregularities, hirsutism or obesity were referred for further laboratory evaluations and abdominal sonography in order to diagnose PCOS and estimate its prevalence. We also aimed to assess the predominant features of this disorder among adolescents. Results The overall prevalence of the syndrome was 3.42%. Out of the 1430 girls, 49 were diagnosed with PCOS. Conclusion Despite its high prevalence, this syndrome has not been widely studied. Most of the conducted studies have enrolled small samples within a short time period. Thus, more accurate policy making in this regard can be achieved through definition of the prevalence of PCOS and accurate estimation of its burden. |
| first_indexed | 2024-12-21T00:40:38Z |
| format | Article |
| id | doaj.art-1076b421a8ec4f84bb2384ca4b845b7f |
| institution | Directory Open Access Journal |
| issn | 2008-076X 2008-0778 |
| language | English |
| last_indexed | 2024-12-21T00:40:38Z |
| publishDate | 2010-10-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj.art-1076b421a8ec4f84bb2384ca4b845b7f2022-12-21T19:21:40ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782010-10-014312212710.22074/ijfs.2010.4580845808Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006Saghar Salehpour0Hamidreza Esmaeilnia Shirvani1Abbas Entezari2Infertility and Reproductive Health Research Center, Taleghani Training Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranShahid Beheshti University of Medical Sciences, Tehran, IranInfertility and Reproductive Health Research Center, Taleghani Training Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IranBackground Polycystic ovarian syndrome (PCOS) was first introduced by Leventhal and Stein in 1935. It has a wide range of manifestations such as hyperandrogenism, irregular menstruation and central body obesity. The lack of definite diagnostic criteria has made the diagnosis a difficult task. Moreover, the disturbing aspects of the syndrome range from hirsutism in an adolescent girl to infertility in a young woman. Based on the Rotterdam 2003 Criteria, current diagnostic criteria must include two of the following three symptoms: 1. Either oligo-ovulation or anovulation, 2. Clinical or laboratory manifestations of hyperandrogenism, 3. Polycystic ovaries on sonographic examination (more than 12 follicles of less than 10 mm in diameter in each ovary). In this study, we have focused on the enrollment of a large sample size to assess the prevalence and clinical features of PCOS such that a wide range of basic information can be utilized for further investigations. Materials and methods This was a cross-sectional study with multi-stage random sampling. Subjects were selected from 15-18 years old girls from a number of high schools in Tehran. After interview and clinical examination, those individuals with either menstrual irregularities, hirsutism or obesity were referred for further laboratory evaluations and abdominal sonography in order to diagnose PCOS and estimate its prevalence. We also aimed to assess the predominant features of this disorder among adolescents. Results The overall prevalence of the syndrome was 3.42%. Out of the 1430 girls, 49 were diagnosed with PCOS. Conclusion Despite its high prevalence, this syndrome has not been widely studied. Most of the conducted studies have enrolled small samples within a short time period. Thus, more accurate policy making in this regard can be achieved through definition of the prevalence of PCOS and accurate estimation of its burden.http://www.ijfs.ir/article_45808_47edddbf4265f8bc11b871ecbae09747.pdf |
| spellingShingle | Saghar Salehpour Hamidreza Esmaeilnia Shirvani Abbas Entezari Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 International Journal of Fertility and Sterility |
| title | Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 |
| title_full | Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 |
| title_fullStr | Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 |
| title_full_unstemmed | Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 |
| title_short | Evaluation of the Prevalence of Polycystic Ovarian Syndrome among Adolescent (15-18 Years Old) Girls in Tehran during 2005-2006 |
| title_sort | evaluation of the prevalence of polycystic ovarian syndrome among adolescent 15 18 years old girls in tehran during 2005 2006 |
| url | http://www.ijfs.ir/article_45808_47edddbf4265f8bc11b871ecbae09747.pdf |
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