Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report
Abstract Background We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successful treatment of this rare condition. Case presentation A 78-year-old wo...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-05-01
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| Series: | BMC Women's Health |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12905-019-0767-5 |
| _version_ | 1818351594237853696 |
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| author | Naoya Ishibashi Toshiya Maebayashi Mikiko Asai-Sato Kei Kawana Masahiro Okada |
| author_facet | Naoya Ishibashi Toshiya Maebayashi Mikiko Asai-Sato Kei Kawana Masahiro Okada |
| author_sort | Naoya Ishibashi |
| collection | DOAJ |
| description | Abstract Background We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successful treatment of this rare condition. Case presentation A 78-year-old woman (gravida 10, para 2, abortion 8) with a 10-year history of uterine prolapse presented for evaluation of bleeding from an ulceration on the surface of the irreducibly prolapsed uterus. Biopsy of a mass on her vaginal wall led to a diagnosis of keratinizing squamous cell carcinoma. Her history of eight abortion procedures had resulted in severe intrauterine adhesions, preventing tandem insertion and intracavitary brachytherapy. She was also ineligible for surgery under general anesthesia + chemotherapy because of her advanced age and presence of arrhythmia. Therefore, we devised an extensive treatment plan involving high-dose-rate interstitial brachytherapy. This treatment successfully eliminated the squamous cell carcinoma as confirmed by biopsy with no recurrence or severe late complications. Conclusions We found that high-dose-rate interstitial brachytherapy may be a very effective therapeutic strategy for this condition with few adverse effects. |
| first_indexed | 2024-12-13T18:40:13Z |
| format | Article |
| id | doaj.art-1077138d8c2f445dbfe2fc07f7dc25ea |
| institution | Directory Open Access Journal |
| issn | 1472-6874 |
| language | English |
| last_indexed | 2024-12-13T18:40:13Z |
| publishDate | 2019-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Women's Health |
| spelling | doaj.art-1077138d8c2f445dbfe2fc07f7dc25ea2022-12-21T23:35:15ZengBMCBMC Women's Health1472-68742019-05-011911710.1186/s12905-019-0767-5Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case reportNaoya Ishibashi0Toshiya Maebayashi1Mikiko Asai-Sato2Kei Kawana3Masahiro Okada4Department of Radiology, Nihon University School of MedicineDepartment of Radiology, Nihon University School of MedicineDepartment of Obstetrics and Gynecology, Nihon University School of MedicineDepartment of Obstetrics and Gynecology, Nihon University School of MedicineDepartment of Radiology, Nihon University School of MedicineAbstract Background We encountered a woman with vaginal cancer that was associated with complete uterine prolapse and complicated by severe intrauterine adhesions. In this case report, we describe the clinical course and successful treatment of this rare condition. Case presentation A 78-year-old woman (gravida 10, para 2, abortion 8) with a 10-year history of uterine prolapse presented for evaluation of bleeding from an ulceration on the surface of the irreducibly prolapsed uterus. Biopsy of a mass on her vaginal wall led to a diagnosis of keratinizing squamous cell carcinoma. Her history of eight abortion procedures had resulted in severe intrauterine adhesions, preventing tandem insertion and intracavitary brachytherapy. She was also ineligible for surgery under general anesthesia + chemotherapy because of her advanced age and presence of arrhythmia. Therefore, we devised an extensive treatment plan involving high-dose-rate interstitial brachytherapy. This treatment successfully eliminated the squamous cell carcinoma as confirmed by biopsy with no recurrence or severe late complications. Conclusions We found that high-dose-rate interstitial brachytherapy may be a very effective therapeutic strategy for this condition with few adverse effects.http://link.springer.com/article/10.1186/s12905-019-0767-5BrachytherapyVaginal cancerUterine prolapseIntrauterine adhesion |
| spellingShingle | Naoya Ishibashi Toshiya Maebayashi Mikiko Asai-Sato Kei Kawana Masahiro Okada Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report BMC Women's Health Brachytherapy Vaginal cancer Uterine prolapse Intrauterine adhesion |
| title | Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report |
| title_full | Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report |
| title_fullStr | Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report |
| title_full_unstemmed | Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report |
| title_short | Radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion: a case report |
| title_sort | radiation therapy for vaginal cancer in complete uterine prolapse with intrauterine adhesion a case report |
| topic | Brachytherapy Vaginal cancer Uterine prolapse Intrauterine adhesion |
| url | http://link.springer.com/article/10.1186/s12905-019-0767-5 |
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