Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay.

Impairment of IFN-gamma response to synthetic peptides of Mycobacterium tuberculosis in a 7-day whole blood assay.

Studies on Mycobacterium tuberculosis (MTB) antigens are of interest in order to improve vaccine efficacy and to define biomarkers for diagnosis and treatment monitoring. The methodologies used for these investigations differ greatly between laboratories and discordant results are common. The IFN-ga...

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Bibliographic Details
Main Authors: Hannah Priyadarshini Gideon, Melissa Shea Hamilton, Kathryn Wood, Dominique Pepper, Tolu Oni, Ronnett Seldon, Claire Banwell, Paul R Langford, Robert J Wilkinson, Katalin A Wilkinson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3738639?pdf=render

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