A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual

Neurofibroma is an uncommon benign tumour of neural tissue origin rarely presenting in the mouth and jaws and thereby attracting the attention of oral physicians. A 22-year-old male patient reported with a complaint of swelling in left middle one third region of face since 8-10 y which was slowly...

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Main Authors: Ashish M. Warhekar, Panjab V. Wanjari, Arati Chaudhary, Dipti Singh Hada, Radhika Gupta
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2015-04-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/5838/12111_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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author Ashish M. Warhekar
Panjab V. Wanjari
Arati Chaudhary
Dipti Singh Hada
Radhika Gupta
author_facet Ashish M. Warhekar
Panjab V. Wanjari
Arati Chaudhary
Dipti Singh Hada
Radhika Gupta
author_sort Ashish M. Warhekar
collection DOAJ
description Neurofibroma is an uncommon benign tumour of neural tissue origin rarely presenting in the mouth and jaws and thereby attracting the attention of oral physicians. A 22-year-old male patient reported with a complaint of swelling in left middle one third region of face since 8-10 y which was slowly progressive in size. He had history of multiple dark brown pigmentation on skin associated with progressively enlarging multiple small nodular growths over the body and single firm nodular growth in left side of maxilla intraorally. He had history of tuberculosis at the age of one year which was treated completely and since last 2-3 y he was suffering from recurrent episodes of sore throat, fever, diarrhea, abdominal pain with vomiting and excessive weight loss. Radiographic findings showed irregular osteolytic lesions involving ramus and angle of mandible, zygomatic bone and posterior part of maxilla with displacement of teeth with abnormal soft tissue enhancement observed by advance imaging. On serological investigation he was HIV positive and histopathologically, diagnosed with Neurofibromatosis-1. Oral manifestations of neurofibromatosis have been reported in only 4% to 7% of affected persons. This article presents a rarest of rare case report of neurofibromatosis-I in HIV positive individual also involving maxilla, mandible as well as zygomatic arch.
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spelling doaj.art-1081707130424c9eb0f85f5bc2276cb62022-12-21T18:49:18ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2015-04-0194ZD20ZD2210.7860/JCDR/2015/12111.5838A Rare Case Report of Neurofibromatosis I in Hiv Positive IndividualAshish M. Warhekar0Panjab V. Wanjari1Arati Chaudhary2Dipti Singh Hada3Radhika Gupta4Reader, Department of Oral Medicine and Maxillofacial Radiology, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India.Professor & Head, Department of Oral Medicine and Maxillofacial Radiology, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India.Professor, Department of Oral Medicine and Maxillofacial Radiology, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India.Senoir Lecturer, Department of Oral Medicine and Maxillofacial Radiology, Sardar Patel Post Graduate Institute of Dental and Medical Sciences, Lucknow, Uttar Pradesh, India.PG Student, Department of Oral Medicine and Maxillofacial Radiology, Modern Dental College & Research Centre, Indore, Madhya Pradesh, India.Neurofibroma is an uncommon benign tumour of neural tissue origin rarely presenting in the mouth and jaws and thereby attracting the attention of oral physicians. A 22-year-old male patient reported with a complaint of swelling in left middle one third region of face since 8-10 y which was slowly progressive in size. He had history of multiple dark brown pigmentation on skin associated with progressively enlarging multiple small nodular growths over the body and single firm nodular growth in left side of maxilla intraorally. He had history of tuberculosis at the age of one year which was treated completely and since last 2-3 y he was suffering from recurrent episodes of sore throat, fever, diarrhea, abdominal pain with vomiting and excessive weight loss. Radiographic findings showed irregular osteolytic lesions involving ramus and angle of mandible, zygomatic bone and posterior part of maxilla with displacement of teeth with abnormal soft tissue enhancement observed by advance imaging. On serological investigation he was HIV positive and histopathologically, diagnosed with Neurofibromatosis-1. Oral manifestations of neurofibromatosis have been reported in only 4% to 7% of affected persons. This article presents a rarest of rare case report of neurofibromatosis-I in HIV positive individual also involving maxilla, mandible as well as zygomatic arch.https://jcdr.net/articles/PDF/5838/12111_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdfaidsneurofibromapanoramic radiograph
spellingShingle Ashish M. Warhekar
Panjab V. Wanjari
Arati Chaudhary
Dipti Singh Hada
Radhika Gupta
A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
Journal of Clinical and Diagnostic Research
aids
neurofibroma
panoramic radiograph
title A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
title_full A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
title_fullStr A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
title_full_unstemmed A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
title_short A Rare Case Report of Neurofibromatosis I in Hiv Positive Individual
title_sort rare case report of neurofibromatosis i in hiv positive individual
topic aids
neurofibroma
panoramic radiograph
url https://jcdr.net/articles/PDF/5838/12111_CE(RA1)_F(T)_PF1(AGAK)_PFA(AK)_PF2(PAG).pdf
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