Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic

The Coronavirus Disease-2019 (COVID-19) is a highly contagious disease presenting with multiple non specific symptoms and caused by Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Despite its dissemination and worsening trends researchers are still searching for the best treatment opti...

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Main Authors: Sunil Shewale, Vaishali Undale, Sameer Parekh, Pramod Pujari, Maruti Shelar, Sohan Chitlange
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2021-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/15257/49181_CE[Ra1]_F[SK]_PF1(SC_OM)_PFA(SC_KM)_PN(KM).pdf
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author Sunil Shewale
Vaishali Undale
Sameer Parekh
Pramod Pujari
Maruti Shelar
Sohan Chitlange
author_facet Sunil Shewale
Vaishali Undale
Sameer Parekh
Pramod Pujari
Maruti Shelar
Sohan Chitlange
author_sort Sunil Shewale
collection DOAJ
description The Coronavirus Disease-2019 (COVID-19) is a highly contagious disease presenting with multiple non specific symptoms and caused by Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Despite its dissemination and worsening trends researchers are still searching for the best treatment option. Timely diagnosis is the key to get more appropriate treatment regimen. Several clinical trials are ongoing to determine the efficacy and safety of existing and new therapies against Coronavirus Disease -2019 (COVID-19). These include corticosteroids, antivirals, monoclonal antibodies, interferon Alpha 2b and other immune modulators. In addition to treatment, efficacious and safe vaccines are required to slow viral transmission and to prevent further morbidity and mortality. The vaccination is useful tool to get control over the virus. Although, mass immunisation campaigns are ongoing in many countries, global coverage is crucial for getting the pandemic under control. This descriptive review collated the information on current diagnostics tools for determination of COVID-19 infection and available preventive and therapeutic strategies based on the ongoing clinical trials data and published literature.
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spelling doaj.art-10820b42ba564bfb9f303c607f10bde42022-12-21T19:22:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2021-08-01158LE01LE0810.7860/JCDR/2021/49181.15257Hype and Hope of Emerging Therapies to Safeguard against COVID-19 PandemicSunil Shewale0Vaishali Undale1Sameer Parekh2Pramod Pujari3 Maruti Shelar4Sohan Chitlange5Research Student, Department of Pharmacology, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.Head, Department of Pharmacology, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.Assistant General Manager, Department of Clinical Research and Pharmacovigilance, Serum Institute of India Pvt. Ltd. Pune, Maharashtra, India.Senior Manager, Department of Clinical Research and Pharmacovigilance, Serum Institute of India Pvt. Ltd. Pune, Maharashtra, India.Assistant Professor, Department of Pharmacognosy Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.Principal, Department of Pharmaceutical Chemistry, Dr. D.Y. Patil Institute of Pharmaceutical Sciences and Research, Pune, Maharashtra, India.The Coronavirus Disease-2019 (COVID-19) is a highly contagious disease presenting with multiple non specific symptoms and caused by Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2). Despite its dissemination and worsening trends researchers are still searching for the best treatment option. Timely diagnosis is the key to get more appropriate treatment regimen. Several clinical trials are ongoing to determine the efficacy and safety of existing and new therapies against Coronavirus Disease -2019 (COVID-19). These include corticosteroids, antivirals, monoclonal antibodies, interferon Alpha 2b and other immune modulators. In addition to treatment, efficacious and safe vaccines are required to slow viral transmission and to prevent further morbidity and mortality. The vaccination is useful tool to get control over the virus. Although, mass immunisation campaigns are ongoing in many countries, global coverage is crucial for getting the pandemic under control. This descriptive review collated the information on current diagnostics tools for determination of COVID-19 infection and available preventive and therapeutic strategies based on the ongoing clinical trials data and published literature.https://jcdr.net/articles/PDF/15257/49181_CE[Ra1]_F[SK]_PF1(SC_OM)_PFA(SC_KM)_PN(KM).pdfcoronavirus disease-2019diagnostic toolstreatmentvaccines
spellingShingle Sunil Shewale
Vaishali Undale
Sameer Parekh
Pramod Pujari
Maruti Shelar
Sohan Chitlange
Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
Journal of Clinical and Diagnostic Research
coronavirus disease-2019
diagnostic tools
treatment
vaccines
title Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
title_full Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
title_fullStr Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
title_full_unstemmed Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
title_short Hype and Hope of Emerging Therapies to Safeguard against COVID-19 Pandemic
title_sort hype and hope of emerging therapies to safeguard against covid 19 pandemic
topic coronavirus disease-2019
diagnostic tools
treatment
vaccines
url https://jcdr.net/articles/PDF/15257/49181_CE[Ra1]_F[SK]_PF1(SC_OM)_PFA(SC_KM)_PN(KM).pdf
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