Modulation of GABAergic Synaptic Transmission by NMDA Receptors in the Dorsal Horn of the Spinal Cord
The dorsal horn (DH) of the spinal cord is an important structure involved in the integration of nociceptive messages. Plastic changes in the properties of neuronal networks in the DH underlie the development of analgesia as well as of hyperalgesia and allodynia in acute and chronic pain states. Two...
Main Authors: | Benjamin Leonardon, Lou Cathenaut, Louise Vial-Markiewicz, Sylvain Hugel, Rémy Schlichter, Perrine Inquimbert |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-07-01
|
Series: | Frontiers in Molecular Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnmol.2022.903087/full |
Similar Items
-
NMDA Receptor Activation Underlies the Loss of Spinal Dorsal Horn Neurons and the Transition to Persistent Pain after Peripheral Nerve Injury
by: Perrine Inquimbert, et al.
Published: (2018-05-01) -
Resolvin D1 reverses chronic pancreatitis-induced mechanical allodynia, phosphorylation of NMDA receptors, and cytokines expression in the thoracic spinal dorsal horn
by: Quan-Xin Feng, et al.
Published: (2012-10-01) -
Anti-allodynic and promotive effect on inhibitory synaptic transmission of riluzole in rat spinal dorsal horn
by: Ryo Taiji, et al.
Published: (2021-12-01) -
Age-dependent decrease in inhibitory drive on the excitatory superficial spinal dorsal horn neurons
by: Prudhvi Raj Rayi, et al.
Published: (2023-08-01) -
Spinal PAR2 Activation Contributes to Hypersensitivity Induced by Peripheral Inflammation in Rats
by: Petra Mrozkova, et al.
Published: (2021-01-01)