Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy
Background: Prostatectomy is associated with short- and long-term morbidity, which includes attenuation of muscle function and deterioration of lean body mass. Physical function is a known predictor of morbidity and mortality, with initial evidence indicating that presurgical exercise is associated...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2017-09-01
|
| Series: | Integrative Cancer Therapies |
| Online Access: | https://doi.org/10.1177/1534735416666373 |
| _version_ | 1830353831403192320 |
|---|---|
| author | Favil Singh PhD Robert U. Newton PhD Michael K. Baker PhD Nigel A. Spry MBBS, PhD Dennis R. Taaffe PhD Jeffery Thavaseelan MBBS Daniel A. Galvão PhD |
| author_facet | Favil Singh PhD Robert U. Newton PhD Michael K. Baker PhD Nigel A. Spry MBBS, PhD Dennis R. Taaffe PhD Jeffery Thavaseelan MBBS Daniel A. Galvão PhD |
| author_sort | Favil Singh PhD |
| collection | DOAJ |
| description | Background: Prostatectomy is associated with short- and long-term morbidity, which includes attenuation of muscle function and deterioration of lean body mass. Physical function is a known predictor of morbidity and mortality, with initial evidence indicating that presurgical exercise is associated with fewer postsurgical complications and shorter hospitalization. The aim was to determine the feasibility of a supervised presurgical exercise program for prostate cancer (PCa) patients scheduled for prostatectomy. Methods: Ten men (68+6.4 years old) with localized PCa undertook a 6-week resistance and aerobic exercise program prior surgery. Training was undertaken twice weekly and patients were assessed at baseline, presurgery, and 6 weeks postsurgery. Outcome measures included muscle and physical performance, body composition, urinary incontinence and questionnaire. Results: Muscle strength increased by 7.5% to 24.3% ( P < .05) from baseline to presurgery but decreased to pretraining levels postsurgery, except for knee extensor strength ( P = .247). There were significant improvements ( P < .05) in the 6-m fast walk (9.3%), 400-m walk (7.4%), and chair rise (12.3%) at presurgery. Following surgery, improvements in physical performance were maintained. There was no change in lean or fat mass prior to surgery, but lean mass declined by 2.7 kg ( P = .014) following surgery. There were no adverse effects from the exercise program. Conclusions: Exercise undertaken prior to prostatectomy improved muscle and physical performance, with functional benefits maintained 6 weeks postsurgery. Presurgical exercise for PCa patients has the potential to facilitate recovery by improving physical reserve capacity, especially in men with poor muscle nd physical performance. |
| first_indexed | 2024-12-20T01:20:28Z |
| format | Article |
| id | doaj.art-108510c0752b44d39f7a8b05413fe68f |
| institution | Directory Open Access Journal |
| issn | 1534-7354 1552-695X |
| language | English |
| last_indexed | 2024-12-20T01:20:28Z |
| publishDate | 2017-09-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Integrative Cancer Therapies |
| spelling | doaj.art-108510c0752b44d39f7a8b05413fe68f2022-12-21T19:58:27ZengSAGE PublishingIntegrative Cancer Therapies1534-73541552-695X2017-09-011610.1177/1534735416666373Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing ProstatectomyFavil Singh PhD0Robert U. Newton PhD1Michael K. Baker PhD2Nigel A. Spry MBBS, PhD3Dennis R. Taaffe PhD4Jeffery Thavaseelan MBBS5Daniel A. Galvão PhD6Edith Cowan University, Joondalup, WA, AustraliaEdith Cowan University, Joondalup, WA, AustraliaAustralian Catholic University, NSW, AustraliaUniversity of Western Australia, Nedlands, WA, AustraliaUniversity of Wollongong, NSW, AustraliaSaint John of God Murdoch Hospital, Murdoch, WA, AustraliaEdith Cowan University, Joondalup, WA, AustraliaBackground: Prostatectomy is associated with short- and long-term morbidity, which includes attenuation of muscle function and deterioration of lean body mass. Physical function is a known predictor of morbidity and mortality, with initial evidence indicating that presurgical exercise is associated with fewer postsurgical complications and shorter hospitalization. The aim was to determine the feasibility of a supervised presurgical exercise program for prostate cancer (PCa) patients scheduled for prostatectomy. Methods: Ten men (68+6.4 years old) with localized PCa undertook a 6-week resistance and aerobic exercise program prior surgery. Training was undertaken twice weekly and patients were assessed at baseline, presurgery, and 6 weeks postsurgery. Outcome measures included muscle and physical performance, body composition, urinary incontinence and questionnaire. Results: Muscle strength increased by 7.5% to 24.3% ( P < .05) from baseline to presurgery but decreased to pretraining levels postsurgery, except for knee extensor strength ( P = .247). There were significant improvements ( P < .05) in the 6-m fast walk (9.3%), 400-m walk (7.4%), and chair rise (12.3%) at presurgery. Following surgery, improvements in physical performance were maintained. There was no change in lean or fat mass prior to surgery, but lean mass declined by 2.7 kg ( P = .014) following surgery. There were no adverse effects from the exercise program. Conclusions: Exercise undertaken prior to prostatectomy improved muscle and physical performance, with functional benefits maintained 6 weeks postsurgery. Presurgical exercise for PCa patients has the potential to facilitate recovery by improving physical reserve capacity, especially in men with poor muscle nd physical performance.https://doi.org/10.1177/1534735416666373 |
| spellingShingle | Favil Singh PhD Robert U. Newton PhD Michael K. Baker PhD Nigel A. Spry MBBS, PhD Dennis R. Taaffe PhD Jeffery Thavaseelan MBBS Daniel A. Galvão PhD Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy Integrative Cancer Therapies |
| title | Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy |
| title_full | Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy |
| title_fullStr | Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy |
| title_full_unstemmed | Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy |
| title_short | Feasibility of Presurgical Exercise in Men With Prostate Cancer Undergoing Prostatectomy |
| title_sort | feasibility of presurgical exercise in men with prostate cancer undergoing prostatectomy |
| url | https://doi.org/10.1177/1534735416666373 |
| work_keys_str_mv | AT favilsinghphd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT robertunewtonphd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT michaelkbakerphd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT nigelasprymbbsphd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT dennisrtaaffephd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT jefferythavaseelanmbbs feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy AT danielagalvaophd feasibilityofpresurgicalexerciseinmenwithprostatecancerundergoingprostatectomy |