High Resolution Melting Analysis for Detecting p53 Gene Mutations in Patients with Non-small Cell Lung Cancer

High Resolution Melting Analysis for Detecting p53 Gene Mutations in Patients with Non-small Cell Lung Cancer

Background and objective It has been proven that p53 gene was related to many human cancers. The mutations in p53 gene play an important role in carcinogensis and mostly happened in exon 5-8. The aim of this study is to establish a high resolution melting (HRM) assay to detect p53 mutations from pat...

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Bibliographic Details
Main Authors: Zhihong CHEN, Shejuan AN, Zhi XIE, Honghong YAN, Jianguang CHEN, Jian SU, Xuchao ZHANG, Feiyu NIU, Weibang GUO, Yilong WU
Format: Article
Language:zho
Published: Chinese Anti-Cancer Association; Chinese Antituberculosis Association 2011-10-01
Series:Chinese Journal of Lung Cancer
Subjects:
p53 gene
Mutation
Sequence
Online Access:http://dx.doi.org/10.3779/j.issn.1009-3419.2011.10.01

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