Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced Ultrasound: A Retrospective Study
Purpose Renal lesions are frequent random findings on CT, MRI, and conventional ultrasound. Since they are usually found accidentally, the respective examinations have not been performed optimally to provide a conclusive diagnosis, making a...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Georg Thieme Verlag KG
2021-04-01
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| Series: | Ultrasound International Open |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1522-8969 |
| _version_ | 1818594880922845184 |
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| author | Arash Najafi Michael Wildt Nicolin Hainc Joachim Hohmann |
| author_facet | Arash Najafi Michael Wildt Nicolin Hainc Joachim Hohmann |
| author_sort | Arash Najafi |
| collection | DOAJ |
| description | Purpose Renal lesions are frequent random findings on CT, MRI, and
conventional ultrasound. Since they are usually found accidentally, the
respective examinations have not been performed optimally to provide a
conclusive diagnosis, making additional multiphase contrast-enhanced
examinations necessary. The aim of the study is to correlate CEUS findings with
the final diagnosis and to determine whether it is a suitable method for the
conclusive characterization of undetermined renal lesions.
Materials and Methods All CEUS examinations of focal renal lesions
performed at our institute between 2007 and 2014 were retrospectively examined.
437 patients with a total of 491 lesions and 543 examinations were included. 54
patients had bilateral lesions. One patient had three lesions in one kidney.
Histology was available in 49 cases and follow-ups in 124 cases. The
sensitivity, specificity, positive and negative predictive value as well as
positive and negative likelihood ratios were calculated.
Results There were 54 malignant and 437 benign lesions. The sensitivity
and specificity were 0.981/0.954 overall, 1.000/0.956 for cystic
lesions, 0.977/0.906 for solid lesions, and 0.971/0.071 for the
histologically confirmed lesions. Bosniak classification was consistent in 289
of 301 lesions (96%). Only 12 lesions (3.9%) were falsely
assessed as malignant.
Conclusion CEUS is an appropriate method for the clarification of
undetermined renal lesions. The characterization of cystic lesions according to
Bosniak is adequately possible, especially for potentially malignant lesions
(types III and IV). |
| first_indexed | 2024-12-16T11:07:09Z |
| format | Article |
| id | doaj.art-108c7aeecc7147f0aadc336443cb755d |
| institution | Directory Open Access Journal |
| issn | 2509-596X 2199-7152 |
| language | English |
| last_indexed | 2024-12-16T11:07:09Z |
| publishDate | 2021-04-01 |
| publisher | Georg Thieme Verlag KG |
| record_format | Article |
| series | Ultrasound International Open |
| spelling | doaj.art-108c7aeecc7147f0aadc336443cb755d2022-12-21T22:33:49ZengGeorg Thieme Verlag KGUltrasound International Open2509-596X2199-71522021-04-010701E25E3410.1055/a-1522-8969Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced Ultrasound: A Retrospective StudyArash Najafi0Michael Wildt1Nicolin Hainc2Joachim Hohmann3Department of Radiology and Nuclear Medicine, Canton Hospital Winterthur, Winterthur, SwitzerlandDepartment of Radiology and Nuclear Medicine, University Hospital Basel, Basel, SwitzerlandDepartment of Medical Imaging, Division of Neuroradiology, Toronto Western Hospital, Toronto, CanadaDepartment of Radiology and Nuclear Medicine, Canton Hospital Winterthur, Winterthur, SwitzerlandPurpose Renal lesions are frequent random findings on CT, MRI, and conventional ultrasound. Since they are usually found accidentally, the respective examinations have not been performed optimally to provide a conclusive diagnosis, making additional multiphase contrast-enhanced examinations necessary. The aim of the study is to correlate CEUS findings with the final diagnosis and to determine whether it is a suitable method for the conclusive characterization of undetermined renal lesions. Materials and Methods All CEUS examinations of focal renal lesions performed at our institute between 2007 and 2014 were retrospectively examined. 437 patients with a total of 491 lesions and 543 examinations were included. 54 patients had bilateral lesions. One patient had three lesions in one kidney. Histology was available in 49 cases and follow-ups in 124 cases. The sensitivity, specificity, positive and negative predictive value as well as positive and negative likelihood ratios were calculated. Results There were 54 malignant and 437 benign lesions. The sensitivity and specificity were 0.981/0.954 overall, 1.000/0.956 for cystic lesions, 0.977/0.906 for solid lesions, and 0.971/0.071 for the histologically confirmed lesions. Bosniak classification was consistent in 289 of 301 lesions (96%). Only 12 lesions (3.9%) were falsely assessed as malignant. Conclusion CEUS is an appropriate method for the clarification of undetermined renal lesions. The characterization of cystic lesions according to Bosniak is adequately possible, especially for potentially malignant lesions (types III and IV).http://www.thieme-connect.de/DOI/DOI?10.1055/a-1522-8969ceusrenalbosniakrcccontrast-enhanced ultrasound |
| spellingShingle | Arash Najafi Michael Wildt Nicolin Hainc Joachim Hohmann Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced Ultrasound: A Retrospective Study Ultrasound International Open ceus renal bosniak rcc contrast-enhanced ultrasound |
| title | Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced
Ultrasound: A Retrospective Study |
| title_full | Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced
Ultrasound: A Retrospective Study |
| title_fullStr | Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced
Ultrasound: A Retrospective Study |
| title_full_unstemmed | Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced
Ultrasound: A Retrospective Study |
| title_short | Evaluation of Cystic and Solid Renal Lesions with Contrast-Enhanced
Ultrasound: A Retrospective Study |
| title_sort | evaluation of cystic and solid renal lesions with contrast enhanced ultrasound a retrospective study |
| topic | ceus renal bosniak rcc contrast-enhanced ultrasound |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/a-1522-8969 |
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