Insulin signaling as a therapeutic mechanism of lithium in bipolar disorder
Abstract In this paper, we propose that lithium may exert its therapeutic effect in bipolar disorder by acting on insulin signaling pathways. Specifically, we assess the importance of the phosphatidylinositol 3-kinase/Protein Kinase B (PI3K/Akt) insulin signaling pathway and we assess how the action...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2022-08-01
|
| Series: | Translational Psychiatry |
| Online Access: | https://doi.org/10.1038/s41398-022-02122-6 |