Diverticular disease of the colon: diagnosis, treatment, and prevention of complications
Introduction. Diverticular disease of the colon is one of the most common gastrointestinal diseases. During the last 30–40 years, there has been a “rejuvenation” of the disease. Today, the prevalence of the disease in people under 40 years of age is 5–10%, and therefore the costs of diagnostic testi...
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| Format: | Article |
| Language: | Russian |
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Remedium Group LLC
2022-04-01
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| Series: | Медицинский совет |
| Subjects: | |
| Online Access: | https://www.med-sovet.pro/jour/article/view/6819 |
| _version_ | 1797841475126427648 |
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| author | O. N. Minushkin M. A. Kruchinina E. I. Altukhova Yu. E. Tugova |
| author_facet | O. N. Minushkin M. A. Kruchinina E. I. Altukhova Yu. E. Tugova |
| author_sort | O. N. Minushkin |
| collection | DOAJ |
| description | Introduction. Diverticular disease of the colon is one of the most common gastrointestinal diseases. During the last 30–40 years, there has been a “rejuvenation” of the disease. Today, the prevalence of the disease in people under 40 years of age is 5–10%, and therefore the costs of diagnostic testing and treatment are gradually increasing, which makes the disease socially significant.Aim. To study the clinical features of diverticular disease, the features of diagnosis and treatment, and prophylactic approaches. The specific objectives of the analysis were to study epidemiology; study the role and a necessary minimum set of laboratory diagnostic test methods for the diagnosis of diverticular disease; study the incidence rate of SIBO and its impact on the clinic presentation and treatment; develop an algorithm for the diagnosis, treatment, prevention, and management of patients with diverticular disease.Materials and methods. A total of 195 patients with different forms of diverticular disease were examined. As diagnostic tests, we used blood tests, stool tests, biochemical tests; inflammatory tests: calprotectin, CRP, fibrinogen, ferritin; ultrasound imaging, irrigoscopy, CT, NMR, colonoscopy (if medically required); clinical manifestations at different stages of the course of diverticular disease. 5-aminosalicylates were used to treat exacerbation with inflammation; alpha-normix and motility regulators were used to treat exacerbation without signs of inflammation.Results. On the basis of the study results, we suggested an algorithm for the diagnosis, management and treatment of patients with diverticular disease. According to the particulars of the management, it is reasonable to divide all patients with diverticular disease into three groups: 1) patients who underwent acute diverticulitis; 2) patients with uncomplicated diverticular disease; 3) patients with complicated diverticular disease.Conclusions. The first two groups should be followed up by a gastroenterologist/general practitioner, the third group should be followed up by a surgeon. The patient tested positive for SIBO should receive drugs to eradicate SIBO. The treatment regimens for exacerbation of diverticular disease are proposed. |
| first_indexed | 2024-04-09T16:31:29Z |
| format | Article |
| id | doaj.art-109011d2319445c0b2a87d0324e556ac |
| institution | Directory Open Access Journal |
| issn | 2079-701X 2658-5790 |
| language | Russian |
| last_indexed | 2024-04-09T16:31:29Z |
| publishDate | 2022-04-01 |
| publisher | Remedium Group LLC |
| record_format | Article |
| series | Медицинский совет |
| spelling | doaj.art-109011d2319445c0b2a87d0324e556ac2023-04-23T06:57:04ZrusRemedium Group LLCМедицинский совет2079-701X2658-57902022-04-010610911510.21518/2079-701X-2022-16-6-109-1156124Diverticular disease of the colon: diagnosis, treatment, and prevention of complicationsO. N. Minushkin0M. A. Kruchinina1E. I. Altukhova2Yu. E. Tugova3Central State Medical Academy of Department for Presidential Affairs of the Russian FederationJoint Hospital with Polyclinic of the Office of the President of the Russian FederationJoint Hospital with Polyclinic of the Office of the President of the Russian FederationJoint Hospital with Polyclinic of the Office of the President of the Russian FederationIntroduction. Diverticular disease of the colon is one of the most common gastrointestinal diseases. During the last 30–40 years, there has been a “rejuvenation” of the disease. Today, the prevalence of the disease in people under 40 years of age is 5–10%, and therefore the costs of diagnostic testing and treatment are gradually increasing, which makes the disease socially significant.Aim. To study the clinical features of diverticular disease, the features of diagnosis and treatment, and prophylactic approaches. The specific objectives of the analysis were to study epidemiology; study the role and a necessary minimum set of laboratory diagnostic test methods for the diagnosis of diverticular disease; study the incidence rate of SIBO and its impact on the clinic presentation and treatment; develop an algorithm for the diagnosis, treatment, prevention, and management of patients with diverticular disease.Materials and methods. A total of 195 patients with different forms of diverticular disease were examined. As diagnostic tests, we used blood tests, stool tests, biochemical tests; inflammatory tests: calprotectin, CRP, fibrinogen, ferritin; ultrasound imaging, irrigoscopy, CT, NMR, colonoscopy (if medically required); clinical manifestations at different stages of the course of diverticular disease. 5-aminosalicylates were used to treat exacerbation with inflammation; alpha-normix and motility regulators were used to treat exacerbation without signs of inflammation.Results. On the basis of the study results, we suggested an algorithm for the diagnosis, management and treatment of patients with diverticular disease. According to the particulars of the management, it is reasonable to divide all patients with diverticular disease into three groups: 1) patients who underwent acute diverticulitis; 2) patients with uncomplicated diverticular disease; 3) patients with complicated diverticular disease.Conclusions. The first two groups should be followed up by a gastroenterologist/general practitioner, the third group should be followed up by a surgeon. The patient tested positive for SIBO should receive drugs to eradicate SIBO. The treatment regimens for exacerbation of diverticular disease are proposed.https://www.med-sovet.pro/jour/article/view/6819diverticular diseasetreatmentprevention5-aminosalicylatesantibioticsprebioticsmetabiotics |
| spellingShingle | O. N. Minushkin M. A. Kruchinina E. I. Altukhova Yu. E. Tugova Diverticular disease of the colon: diagnosis, treatment, and prevention of complications Медицинский совет diverticular disease treatment prevention 5-aminosalicylates antibiotics prebiotics metabiotics |
| title | Diverticular disease of the colon: diagnosis, treatment, and prevention of complications |
| title_full | Diverticular disease of the colon: diagnosis, treatment, and prevention of complications |
| title_fullStr | Diverticular disease of the colon: diagnosis, treatment, and prevention of complications |
| title_full_unstemmed | Diverticular disease of the colon: diagnosis, treatment, and prevention of complications |
| title_short | Diverticular disease of the colon: diagnosis, treatment, and prevention of complications |
| title_sort | diverticular disease of the colon diagnosis treatment and prevention of complications |
| topic | diverticular disease treatment prevention 5-aminosalicylates antibiotics prebiotics metabiotics |
| url | https://www.med-sovet.pro/jour/article/view/6819 |
| work_keys_str_mv | AT onminushkin diverticulardiseaseofthecolondiagnosistreatmentandpreventionofcomplications AT makruchinina diverticulardiseaseofthecolondiagnosistreatmentandpreventionofcomplications AT eialtukhova diverticulardiseaseofthecolondiagnosistreatmentandpreventionofcomplications AT yuetugova diverticulardiseaseofthecolondiagnosistreatmentandpreventionofcomplications |