Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods

It is revealed, that pathological changes in the plasmatic and platelets-vascular part of a hemostasis are expressed to a lesser degree in the acute period of the lacunar stroke in comparison with a nonlacunar stroke. Safety of antithrombotic properties of a vascular wall in the given subgroup is co...

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Main Authors: Ye. G. Smertina, S. V. Prokopenko, V. G. Ionova, M. M. Tanashyan, V. V. Potylitsina
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2009-02-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1769
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author Ye. G. Smertina
S. V. Prokopenko
V. G. Ionova
M. M. Tanashyan
V. V. Potylitsina
author_facet Ye. G. Smertina
S. V. Prokopenko
V. G. Ionova
M. M. Tanashyan
V. V. Potylitsina
author_sort Ye. G. Smertina
collection DOAJ
description It is revealed, that pathological changes in the plasmatic and platelets-vascular part of a hemostasis are expressed to a lesser degree in the acute period of the lacunar stroke in comparison with a nonlacunar stroke. Safety of antithrombotic properties of a vascular wall in the given subgroup is confirmed. Dis - tinctions in the hemostasis profile of various pathogenesis types of strokes disappear in the early regenerative period of stroke, lasting haemostatic activation with hyperfirinogenemia, and increase in markers of thrombosis, strengthening of spontaneous platelet’s aggregation, as well as increase of level of a marker endothelium dysfunction remains with the expressed decrease in reactance endothelium.
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spelling doaj.art-10904ff0520e42f89869e9f481687ab72023-03-13T09:58:10ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842009-02-0181(2)727710.20538/1682-0363-2009-1(2)-72-771265Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periodsYe. G. Smertina0S. V. Prokopenko1V. G. Ionova2M. M. Tanashyan3V. V. Potylitsina4Городская больница № 6, НЦ неврологии РАМНКрасноярский государственный медицинский университет им. В.Ф. Войно-ЯсенецкогоНЦ неврологии РАМННЦ неврологии РАМНГородская больница № 6It is revealed, that pathological changes in the plasmatic and platelets-vascular part of a hemostasis are expressed to a lesser degree in the acute period of the lacunar stroke in comparison with a nonlacunar stroke. Safety of antithrombotic properties of a vascular wall in the given subgroup is confirmed. Dis - tinctions in the hemostasis profile of various pathogenesis types of strokes disappear in the early regenerative period of stroke, lasting haemostatic activation with hyperfirinogenemia, and increase in markers of thrombosis, strengthening of spontaneous platelet’s aggregation, as well as increase of level of a marker endothelium dysfunction remains with the expressed decrease in reactance endothelium.https://bulletin.ssmu.ru/jour/article/view/1769ишемический инсультагрегация тромбоцитовманжеточная пробадисфункция эндотелияфактор виллебранда
spellingShingle Ye. G. Smertina
S. V. Prokopenko
V. G. Ionova
M. M. Tanashyan
V. V. Potylitsina
Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
Бюллетень сибирской медицины
ишемический инсульт
агрегация тромбоцитов
манжеточная проба
дисфункция эндотелия
фактор виллебранда
title Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
title_full Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
title_fullStr Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
title_full_unstemmed Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
title_short Hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
title_sort hemostasis system condition and endothelium functions during various pathogenesis types of ischemic strokes in the acute and regenerative periods
topic ишемический инсульт
агрегация тромбоцитов
манжеточная проба
дисфункция эндотелия
фактор виллебранда
url https://bulletin.ssmu.ru/jour/article/view/1769
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AT svprokopenko hemostasissystemconditionandendotheliumfunctionsduringvariouspathogenesistypesofischemicstrokesintheacuteandregenerativeperiods
AT vgionova hemostasissystemconditionandendotheliumfunctionsduringvariouspathogenesistypesofischemicstrokesintheacuteandregenerativeperiods
AT mmtanashyan hemostasissystemconditionandendotheliumfunctionsduringvariouspathogenesistypesofischemicstrokesintheacuteandregenerativeperiods
AT vvpotylitsina hemostasissystemconditionandendotheliumfunctionsduringvariouspathogenesistypesofischemicstrokesintheacuteandregenerativeperiods