Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation
Abstract Vaccination is a highly effective preventive measure against COVID‐19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and TRPA1/V...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-03-01
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| Series: | Clinical and Translational Allergy |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/clt2.12127 |
| _version_ | 1828375321756303360 |
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| author | Jean Bousquet Tari Haahtela Hubert Blain Wienczyslawa Czarlewski Torsten Zuberbier Anna Bedbrook Alvaro A. Cruz Joao A. Fonseca Ludger Klimek Piotr Kuna Boleslaw Samolinski Arunas Valiulis Antoine Lemaire Josep M. Anto |
| author_facet | Jean Bousquet Tari Haahtela Hubert Blain Wienczyslawa Czarlewski Torsten Zuberbier Anna Bedbrook Alvaro A. Cruz Joao A. Fonseca Ludger Klimek Piotr Kuna Boleslaw Samolinski Arunas Valiulis Antoine Lemaire Josep M. Anto |
| author_sort | Jean Bousquet |
| collection | DOAJ |
| description | Abstract Vaccination is a highly effective preventive measure against COVID‐19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID‐19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID‐19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID‐19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double‐blind, placebo‐controlled design. |
| first_indexed | 2024-04-14T07:44:56Z |
| format | Article |
| id | doaj.art-1090ac4b5fd146f7a3e2ec5d2157f925 |
| institution | Directory Open Access Journal |
| issn | 2045-7022 |
| language | English |
| last_indexed | 2024-04-14T07:44:56Z |
| publishDate | 2022-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Translational Allergy |
| spelling | doaj.art-1090ac4b5fd146f7a3e2ec5d2157f9252022-12-22T02:05:21ZengWileyClinical and Translational Allergy2045-70222022-03-01123n/an/a10.1002/clt2.12127Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementationJean Bousquet0Tari Haahtela1Hubert Blain2Wienczyslawa Czarlewski3Torsten Zuberbier4Anna Bedbrook5Alvaro A. Cruz6Joao A. Fonseca7Ludger Klimek8Piotr Kuna9Boleslaw Samolinski10Arunas Valiulis11Antoine Lemaire12Josep M. Anto13Institute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin GermanySkin and Allergy Hospital Helsinki University Hospital University of Helsinki Helsinki FinlandDepartment of Geriatrics Montpellier University Hospital, MUSE Montpellier FranceMASK‐air Montpellier FranceInstitute of Allergology Charité – Universitätsmedizin Berlin Corporate Member of Freie Universität Berlin and Humboldt‐Universität zu Berlin Berlin GermanyMASK‐air Montpellier FranceFundaçao ProAR Federal University of Bahia and GARD/WHO Planning Group Salvador Bahia BrazilDepartment of Community Medicine Information and Health Decision Sciences (MEDCIDS) Faculty of Medicine, University of Porto Porto PortugalDepartment of Otolaryngology, Head and Neck Surgery Wiesbaden GermanyDivision of Internal Medicine, Asthma and Allergy Barlicki University Hospital Medical University of Lodz Lodz PolandDepartment of Prevention of Environmental Hazards, Allergology and Immunology Medical University of Warsaw Warsaw PolandInstitute of Clinical Medicine and Institute of Health Sciences Medical Faculty of Vilnius University Vilnius LithuaniaCentre Hospitalier Valenciennes FranceIMIM (Hospital del Mar Medical Research Institute) Barcelona SpainAbstract Vaccination is a highly effective preventive measure against COVID‐19. However, complementary treatments are needed to better control the disease. Fermented vegetables and spices, agonists of the antioxidant transcription factor nuclear factor (erythroid‐derived 2)‐like 2 (Nrf2) and TRPA1/V1 channels (Transient Receptor Potential Ankyrin 1 and Vanillin 1), may help in the control of COVID‐19. Some preliminary clinical trials suggest that curcumin (spice) can prevent some of the COVID‐19 symptoms. Before any conclusion can be drawn and these treatments recommended for COVID‐19, the data warrant confirmation. In particular, the benefits of the foods need to be assessed in more patients, through research studies and large trials employing a double‐blind, placebo‐controlled design.https://doi.org/10.1002/clt2.12127broccoliCOVID‐19curcuminNrf2TRP channel |
| spellingShingle | Jean Bousquet Tari Haahtela Hubert Blain Wienczyslawa Czarlewski Torsten Zuberbier Anna Bedbrook Alvaro A. Cruz Joao A. Fonseca Ludger Klimek Piotr Kuna Boleslaw Samolinski Arunas Valiulis Antoine Lemaire Josep M. Anto Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation Clinical and Translational Allergy broccoli COVID‐19 curcumin Nrf2 TRP channel |
| title | Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation |
| title_full | Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation |
| title_fullStr | Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation |
| title_full_unstemmed | Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation |
| title_short | Available and affordable complementary treatments for COVID‐19: From hypothesis to pilot studies and the need for implementation |
| title_sort | available and affordable complementary treatments for covid 19 from hypothesis to pilot studies and the need for implementation |
| topic | broccoli COVID‐19 curcumin Nrf2 TRP channel |
| url | https://doi.org/10.1002/clt2.12127 |
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