Actin cytoskeleton regulation of epithelial mesenchymal transition in metastatic cancer cells.

Epithelial-mesenchymal transition (EMT) is associated with loss of the cell-cell adhesion molecule E-cadherin and disruption of cell-cell junctions as well as with acquisition of migratory properties including reorganization of the actin cytoskeleton and activation of the RhoA GTPase. Here we show t...

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Bibliographic Details
Main Authors: Jay Shankar, Ivan R Nabi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4355409?pdf=render

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