Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study
Abstract Background The effects of general anesthesia with deep sedation and conscious sedation have been compared for sedation management in the perioperative period for radiofrequency catheter ablation of the heart to treat atrial fibrillation. However, there is no consensus as to which drug to us...
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| Format: | Article |
| Language: | English |
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BMC
2021-01-01
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| Series: | Journal of Pharmaceutical Health Care and Sciences |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40780-020-00184-6 |
| _version_ | 1819278981298388992 |
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| author | Teruhisa Kinoshita Mitsunori Harada Norio Takimoto Daichi Shibata Takashi Sakakibara Mamoru Adachi |
| author_facet | Teruhisa Kinoshita Mitsunori Harada Norio Takimoto Daichi Shibata Takashi Sakakibara Mamoru Adachi |
| author_sort | Teruhisa Kinoshita |
| collection | DOAJ |
| description | Abstract Background The effects of general anesthesia with deep sedation and conscious sedation have been compared for sedation management in the perioperative period for radiofrequency catheter ablation of the heart to treat atrial fibrillation. However, there is no consensus as to which drug to use for conscious sedation. This study aimed to investigate analgesic and sedative drugs suitable for perioperative ablation. Methods We retrospectively examined 93 patients who underwent atrial fibrillation ablation at Kariya Toyoda General Hospital between December 2017 and April 2019 and investigated differences in the outcomes, such as depth of sedation and postoperative adverse events between the buprenorphine hydrochloride (n = 46) and fentanyl citrate (n = 47) groups. Results The depth of sedation was similar between the two groups, without significant between-group differences in postoperative vomiting. The number of additional injections of thiamylal sodium to manage discomfort and pain during ablation were significantly lower in the fentanyl group. Additionally, the cumulative area product, cumulative total air kerma, 1-year postoperative atrial fibrillation recurrence rate, and postoperative complications were not significantly different between the two groups. Conclusions Although there were no significant differences in the efficacy or safety between buprenorphine hydrochloride and fentanyl citrate as analgesics used during atrial fibrillation ablation, intraoperative body movements and patient discomfort could be reduced to a greater extent with the use of fentanyl. |
| first_indexed | 2024-12-24T00:20:38Z |
| format | Article |
| id | doaj.art-109f64103bcb4012ac3492e7d6983e72 |
| institution | Directory Open Access Journal |
| issn | 2055-0294 |
| language | English |
| last_indexed | 2024-12-24T00:20:38Z |
| publishDate | 2021-01-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Pharmaceutical Health Care and Sciences |
| spelling | doaj.art-109f64103bcb4012ac3492e7d6983e722022-12-21T17:24:35ZengBMCJournal of Pharmaceutical Health Care and Sciences2055-02942021-01-01711610.1186/s40780-020-00184-6Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional studyTeruhisa Kinoshita0Mitsunori Harada1Norio Takimoto2Daichi Shibata3Takashi Sakakibara4Mamoru Adachi5Department of Pharmacy, Kariya Toyota General HospitalDepartment of Cardiology, Kariya Toyota General HospitalDepartment of Pharmacy, Kariya Toyota General HospitalDepartment of Pharmacy, Kariya Toyota General HospitalDepartment of Pharmacy, Kariya Toyota General HospitalDepartment of Pharmacy, Kariya Toyota General HospitalAbstract Background The effects of general anesthesia with deep sedation and conscious sedation have been compared for sedation management in the perioperative period for radiofrequency catheter ablation of the heart to treat atrial fibrillation. However, there is no consensus as to which drug to use for conscious sedation. This study aimed to investigate analgesic and sedative drugs suitable for perioperative ablation. Methods We retrospectively examined 93 patients who underwent atrial fibrillation ablation at Kariya Toyoda General Hospital between December 2017 and April 2019 and investigated differences in the outcomes, such as depth of sedation and postoperative adverse events between the buprenorphine hydrochloride (n = 46) and fentanyl citrate (n = 47) groups. Results The depth of sedation was similar between the two groups, without significant between-group differences in postoperative vomiting. The number of additional injections of thiamylal sodium to manage discomfort and pain during ablation were significantly lower in the fentanyl group. Additionally, the cumulative area product, cumulative total air kerma, 1-year postoperative atrial fibrillation recurrence rate, and postoperative complications were not significantly different between the two groups. Conclusions Although there were no significant differences in the efficacy or safety between buprenorphine hydrochloride and fentanyl citrate as analgesics used during atrial fibrillation ablation, intraoperative body movements and patient discomfort could be reduced to a greater extent with the use of fentanyl.https://doi.org/10.1186/s40780-020-00184-6Atrial fibrillationBuprenorphine hydrochlorideCatheter ablationFentanyl citrate |
| spellingShingle | Teruhisa Kinoshita Mitsunori Harada Norio Takimoto Daichi Shibata Takashi Sakakibara Mamoru Adachi Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study Journal of Pharmaceutical Health Care and Sciences Atrial fibrillation Buprenorphine hydrochloride Catheter ablation Fentanyl citrate |
| title | Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study |
| title_full | Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study |
| title_fullStr | Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study |
| title_full_unstemmed | Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study |
| title_short | Fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation: a retrospective cross-sectional study |
| title_sort | fentanyl compared to buprenorphine for atrial fibrillation ablation analgesia and sedation a retrospective cross sectional study |
| topic | Atrial fibrillation Buprenorphine hydrochloride Catheter ablation Fentanyl citrate |
| url | https://doi.org/10.1186/s40780-020-00184-6 |
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