Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country.
OBJECTIVES: Clinical characteristics and trends in the outcome of acute coronary syndrome (ACS) in patients with prior coronary artery bypass graft surgery (CABG) are unclear. The aim of this study was to evaluate clinical characteristics, in-hospital treatment, and outcomes in patients presented wi...
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
|
| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC3399890?pdf=render |
| _version_ | 1819120855738744832 |
|---|---|
| author | Rafid Al-Aqeedi Nidal Asaad Awad Al-Qahtani Rajvir Singh Hajar A Al Binali Abdul Wahid Al Mulla Jassim Al Suwaidi |
| author_facet | Rafid Al-Aqeedi Nidal Asaad Awad Al-Qahtani Rajvir Singh Hajar A Al Binali Abdul Wahid Al Mulla Jassim Al Suwaidi |
| author_sort | Rafid Al-Aqeedi |
| collection | DOAJ |
| description | OBJECTIVES: Clinical characteristics and trends in the outcome of acute coronary syndrome (ACS) in patients with prior coronary artery bypass graft surgery (CABG) are unclear. The aim of this study was to evaluate clinical characteristics, in-hospital treatment, and outcomes in patients presented with ACS with or without a history of prior CABG over 2 decades. METHODS: Data were derived from hospital-based study for collected data from 1991 through 2010 of patients hospitalized with ACS in Doha, Qatar. Data were analyzed according to their history of prior CABG. Baseline clinical characteristics, in-hospital treatment, and outcome were compared. RESULTS: A total 16,750 consecutive patients with ACS were studied, of which 693 (4.1%) had prior CABG. Patients with prior CABG were older (mean 60.5±11 vs. 53±12 years; P = 0.001), more likely to be females and have more cardiovascular risk factors than the non-CABG group. Prior CABG patients had larger infarct size, were less likely to receive reperfusion therapy, early invasive therapy and more likely to receive evidence-based therapies when compared to non-CABG patients. In-hospital mortality and stroke rates were comparable between the 2 groups. Over 2 decades, there was reduction in the in-hospital mortality rates and stroke rates in both groups (CABG, death; 13.2% to 4%, stroke; 1.9% to 0.0%, non-CABG, death; 10% to 3.2%, stroke 1.0% to 0.1%; all, p = 0.001). CONCLUSION: Significant reduction in-hospital morbidity and mortality among ACS patients with prior CABG over a 20-year period. |
| first_indexed | 2024-12-22T06:27:18Z |
| format | Article |
| id | doaj.art-10a0818bcaf3428db7096ea75a2e2dc4 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T06:27:18Z |
| publishDate | 2012-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-10a0818bcaf3428db7096ea75a2e2dc42022-12-21T18:35:49ZengPublic Library of Science (PLoS)PLoS ONE1932-62032012-01-0177e4057110.1371/journal.pone.0040571Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country.Rafid Al-AqeediNidal AsaadAwad Al-QahtaniRajvir SinghHajar A Al BinaliAbdul Wahid Al MullaJassim Al SuwaidiOBJECTIVES: Clinical characteristics and trends in the outcome of acute coronary syndrome (ACS) in patients with prior coronary artery bypass graft surgery (CABG) are unclear. The aim of this study was to evaluate clinical characteristics, in-hospital treatment, and outcomes in patients presented with ACS with or without a history of prior CABG over 2 decades. METHODS: Data were derived from hospital-based study for collected data from 1991 through 2010 of patients hospitalized with ACS in Doha, Qatar. Data were analyzed according to their history of prior CABG. Baseline clinical characteristics, in-hospital treatment, and outcome were compared. RESULTS: A total 16,750 consecutive patients with ACS were studied, of which 693 (4.1%) had prior CABG. Patients with prior CABG were older (mean 60.5±11 vs. 53±12 years; P = 0.001), more likely to be females and have more cardiovascular risk factors than the non-CABG group. Prior CABG patients had larger infarct size, were less likely to receive reperfusion therapy, early invasive therapy and more likely to receive evidence-based therapies when compared to non-CABG patients. In-hospital mortality and stroke rates were comparable between the 2 groups. Over 2 decades, there was reduction in the in-hospital mortality rates and stroke rates in both groups (CABG, death; 13.2% to 4%, stroke; 1.9% to 0.0%, non-CABG, death; 10% to 3.2%, stroke 1.0% to 0.1%; all, p = 0.001). CONCLUSION: Significant reduction in-hospital morbidity and mortality among ACS patients with prior CABG over a 20-year period.http://europepmc.org/articles/PMC3399890?pdf=render |
| spellingShingle | Rafid Al-Aqeedi Nidal Asaad Awad Al-Qahtani Rajvir Singh Hajar A Al Binali Abdul Wahid Al Mulla Jassim Al Suwaidi Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. PLoS ONE |
| title | Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. |
| title_full | Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. |
| title_fullStr | Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. |
| title_full_unstemmed | Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. |
| title_short | Acute coronary syndrome in patients with prior coronary artery bypass surgery: observations from a 20-year registry in a middle-eastern country. |
| title_sort | acute coronary syndrome in patients with prior coronary artery bypass surgery observations from a 20 year registry in a middle eastern country |
| url | http://europepmc.org/articles/PMC3399890?pdf=render |
| work_keys_str_mv | AT rafidalaqeedi acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT nidalasaad acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT awadalqahtani acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT rajvirsingh acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT hajaraalbinali acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT abdulwahidalmulla acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry AT jassimalsuwaidi acutecoronarysyndromeinpatientswithpriorcoronaryarterybypasssurgeryobservationsfroma20yearregistryinamiddleeasterncountry |