A new primer construction technique that effectively increases amplification of rare mutant templates in samples
Abstract Background In personalized medicine, companion diagnostic tests provide additional information to help select a treatment option likely to be optimal for a patient. Although such tests include several techniques for detecting low levels of mutant genes in wild-type backgrounds with fairly h...
Main Authors: | Jr-Kai Huang, Ling Fan, Tao-Yeuan Wang, Pao-Shu Wu |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-08-01
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Series: | BMC Biotechnology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12896-019-0555-1 |
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