Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report
Herpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises 20-50% of inflammatory diseases in the cornea. Since keratitis is characterized by a long-term duration, severity, and a tendency to recurrence, studies on ophthalmic herpes and searches for new treatments are of great r...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Ukrainian Society of Ophthalmologists
2019-02-01
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| Series: | Journal of Ophthalmology |
| Subjects: | |
| Online Access: | https://www.ozhurnal.com/en/archive/2019/1/11-fulltext |
| _version_ | 1797384523113037824 |
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| author | L.F. Troychenko T.B. Gaydamaka G.I. Drozhzhyna |
| author_facet | L.F. Troychenko T.B. Gaydamaka G.I. Drozhzhyna |
| author_sort | L.F. Troychenko |
| collection | DOAJ |
| description | Herpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises 20-50% of inflammatory diseases in the cornea. Since keratitis is characterized by a long-term duration, severity, and a tendency to recurrence, studies on ophthalmic herpes and searches for new treatments are of great relevance.
Our clinical case demonstrated successful combined treatment of a recurrent stromal herpetic corneal lesion with ulceration. Both treatments, conservative (complex etiotropic, anti-viral, anti-inflammatory, and nutrition-improving) and surgical (an onlay technique), were successful. At 12 months after surgery, the patients had no pain syndrome; the corneal surface was epithelialized. No recurrence of herpetic keratitis was observed.
Thus, a combination of etiotropic pathogenic treatment and AM transplantation appears to be effective for severe long-lasting recurrent herpetic keratitis with the presence of defects on the corneal surface. |
| first_indexed | 2024-03-08T21:36:48Z |
| format | Article |
| id | doaj.art-10a9989d3d5a4725a97a33c4621fe2aa |
| institution | Directory Open Access Journal |
| issn | 2412-8740 |
| language | English |
| last_indexed | 2024-03-08T21:36:48Z |
| publishDate | 2019-02-01 |
| publisher | Ukrainian Society of Ophthalmologists |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj.art-10a9989d3d5a4725a97a33c4621fe2aa2023-12-20T21:43:32ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402019-02-011616410.31288/oftalmolzh201916164Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case ReportL.F. Troychenko0T.B. Gaydamaka1G.I. Drozhzhyna2Filatov Institute of Eye Diseases and Tissue Therapy, NAMS of UkraineFilatov Institute of Eye Diseases and Tissue Therapy, NAMS of UkraineFilatov Institute of Eye Diseases and Tissue Therapy, NAMS of UkraineHerpes simplex keratitis (HSK) is a severe ophthalmic pathology which comprises 20-50% of inflammatory diseases in the cornea. Since keratitis is characterized by a long-term duration, severity, and a tendency to recurrence, studies on ophthalmic herpes and searches for new treatments are of great relevance. Our clinical case demonstrated successful combined treatment of a recurrent stromal herpetic corneal lesion with ulceration. Both treatments, conservative (complex etiotropic, anti-viral, anti-inflammatory, and nutrition-improving) and surgical (an onlay technique), were successful. At 12 months after surgery, the patients had no pain syndrome; the corneal surface was epithelialized. No recurrence of herpetic keratitis was observed. Thus, a combination of etiotropic pathogenic treatment and AM transplantation appears to be effective for severe long-lasting recurrent herpetic keratitis with the presence of defects on the corneal surface.https://www.ozhurnal.com/en/archive/2019/1/11-fulltextherpetic keratitistreatment |
| spellingShingle | L.F. Troychenko T.B. Gaydamaka G.I. Drozhzhyna Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report Journal of Ophthalmology herpetic keratitis treatment |
| title | Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report |
| title_full | Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report |
| title_fullStr | Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report |
| title_full_unstemmed | Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report |
| title_short | Combined Treatment for Recurrent Herpetic Stromal Keratitis with Ulceration: a Case Report |
| title_sort | combined treatment for recurrent herpetic stromal keratitis with ulceration a case report |
| topic | herpetic keratitis treatment |
| url | https://www.ozhurnal.com/en/archive/2019/1/11-fulltext |
| work_keys_str_mv | AT lftroychenko combinedtreatmentforrecurrentherpeticstromalkeratitiswithulcerationacasereport AT tbgaydamaka combinedtreatmentforrecurrentherpeticstromalkeratitiswithulcerationacasereport AT gidrozhzhyna combinedtreatmentforrecurrentherpeticstromalkeratitiswithulcerationacasereport |