Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

Flexible neural networks, such as the interconnected spinal neurons that control distinct motor actions, can switch their activity to produce different behaviors. Both excitatory (E) and inhibitory (I) spinal neurons are necessary for motor behavior, but the influence of recruiting different ratios...

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Bibliographic Details
Main Authors: Matthew J Sternfeld, Christopher A Hinckley, Niall J Moore, Matthew T Pankratz, Kathryn L Hilde, Shawn P Driscoll, Marito Hayashi, Neal D Amin, Dario Bonanomi, Wesley D Gifford, Kamal Sharma, Martyn Goulding, Samuel L Pfaff
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-02-01
Series:eLife
Subjects:
circuitoid
synthetic network
excitatory-inhibitory balance
embryonic stem cells
rhythmicity
Online Access:https://elifesciences.org/articles/21540

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