Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis
Objective: We investigated the usefulness of 2D-perfusion analysis for the evaluation of cerebral blood flow in unilateral cervical internal carotid artery stenosis. Methods: We conducted a 2D-perfusion analysis during cerebral angiography and 123I-iodoamphetamine (IMP) single photon emission comput...
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| Format: | Article |
| Language: | English |
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The Japanese Society for Neuroendovascular Therapy
2021-01-01
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| Series: | JNET |
| Subjects: | |
| Online Access: | https://www.jstage.jst.go.jp/article/jnet/15/9/15_oa.2020-0132/_pdf/-char/en |
| _version_ | 1818741859975954432 |
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| author | Akifumi Yoshikawa Takehiro Uno Iku Nambu Tomoya Kamide Kouichi Misaki Mitsutoshi Nakada |
| author_facet | Akifumi Yoshikawa Takehiro Uno Iku Nambu Tomoya Kamide Kouichi Misaki Mitsutoshi Nakada |
| author_sort | Akifumi Yoshikawa |
| collection | DOAJ |
| description | Objective: We investigated the usefulness of 2D-perfusion analysis for the evaluation of cerebral blood flow in unilateral cervical internal carotid artery stenosis. Methods: We conducted a 2D-perfusion analysis during cerebral angiography and 123I-iodoamphetamine (IMP) single photon emission computed tomography (SPECT) for unilateral cervical internal carotid artery stenosis without contralateral stenosis. The relationship between the ratio of the lesion side to the normal side in the parameters obtained by 2D-perfusion and the value calculated by stereotactic extraction estimation (SEE) analysis of SPECT was statistically examined.Results: The ratios of the lesion side to the normal side regarding the peak arrival time (AT; time to peak [TTP]) of the contrast agent and the mean filling time (mean transit time [MTT]) of the contrast agent in 2D-perfusion significantly correlated with the area of Stage II and increase ratio (I.R) ≤30% in the SEE analysis (p = 0.002, 0.003). Conclusion: 2D-perfusion analysis can be used to estimate the extent of impaired cerebrovascular reserve (CVR) area in unilateral internal carotid artery stenosis. |
| first_indexed | 2024-12-18T02:03:20Z |
| format | Article |
| id | doaj.art-10b45b4310ec450aa5024721c79bb62b |
| institution | Directory Open Access Journal |
| issn | 1882-4072 2186-2494 |
| language | English |
| last_indexed | 2024-12-18T02:03:20Z |
| publishDate | 2021-01-01 |
| publisher | The Japanese Society for Neuroendovascular Therapy |
| record_format | Article |
| series | JNET |
| spelling | doaj.art-10b45b4310ec450aa5024721c79bb62b2022-12-21T21:24:40ZengThe Japanese Society for Neuroendovascular TherapyJNET1882-40722186-24942021-01-0115958358810.5797/jnet.oa.2020-0132jnetUsefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery StenosisAkifumi Yoshikawa0Takehiro Uno1Iku Nambu2Tomoya Kamide3Kouichi Misaki4Mitsutoshi Nakada5Department of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanDepartment of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanDepartment of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanDepartment of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanDepartment of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanDepartment of Neurosurgery, University of Kanazawa, Kanazawa, Ishikawa, JapanObjective: We investigated the usefulness of 2D-perfusion analysis for the evaluation of cerebral blood flow in unilateral cervical internal carotid artery stenosis. Methods: We conducted a 2D-perfusion analysis during cerebral angiography and 123I-iodoamphetamine (IMP) single photon emission computed tomography (SPECT) for unilateral cervical internal carotid artery stenosis without contralateral stenosis. The relationship between the ratio of the lesion side to the normal side in the parameters obtained by 2D-perfusion and the value calculated by stereotactic extraction estimation (SEE) analysis of SPECT was statistically examined.Results: The ratios of the lesion side to the normal side regarding the peak arrival time (AT; time to peak [TTP]) of the contrast agent and the mean filling time (mean transit time [MTT]) of the contrast agent in 2D-perfusion significantly correlated with the area of Stage II and increase ratio (I.R) ≤30% in the SEE analysis (p = 0.002, 0.003). Conclusion: 2D-perfusion analysis can be used to estimate the extent of impaired cerebrovascular reserve (CVR) area in unilateral internal carotid artery stenosis.https://www.jstage.jst.go.jp/article/jnet/15/9/15_oa.2020-0132/_pdf/-char/eninternal carotid artery stenosis2d-perfusiondigital subtraction angiographysingle photon emission computed tomographycerebrovascular reserve |
| spellingShingle | Akifumi Yoshikawa Takehiro Uno Iku Nambu Tomoya Kamide Kouichi Misaki Mitsutoshi Nakada Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis JNET internal carotid artery stenosis 2d-perfusion digital subtraction angiography single photon emission computed tomography cerebrovascular reserve |
| title | Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis |
| title_full | Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis |
| title_fullStr | Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis |
| title_full_unstemmed | Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis |
| title_short | Usefulness of 2D-Perfusion Analysis for the Assessment of Unilateral Cervical Internal Carotid Artery Stenosis |
| title_sort | usefulness of 2d perfusion analysis for the assessment of unilateral cervical internal carotid artery stenosis |
| topic | internal carotid artery stenosis 2d-perfusion digital subtraction angiography single photon emission computed tomography cerebrovascular reserve |
| url | https://www.jstage.jst.go.jp/article/jnet/15/9/15_oa.2020-0132/_pdf/-char/en |
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