Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty
AimsThe aim of this study was to report the meaningful values of the EuroQol five-dimension three-level questionnaire (EQ-5D-3L) and EuroQol visual analogue scale (EQ-VAS) in patients undergoing primary knee arthroplasty (KA).MethodsThis is a retrospective study of patients undergoing primary KA for...
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| Format: | Article |
| Language: | English |
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The British Editorial Society of Bone & Joint Surgery
2022-09-01
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| Series: | Bone & Joint Research |
| Subjects: | |
| Online Access: | https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.119.BJR-2022-0054.R1 |
| _version_ | 1798001315166552064 |
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| author | Liam Z. Yapp Chloe E. H. Scott Colin R. Howie Deborah J. MacDonald A. Hamish R. W. Simpson Nick D. Clement |
| author_facet | Liam Z. Yapp Chloe E. H. Scott Colin R. Howie Deborah J. MacDonald A. Hamish R. W. Simpson Nick D. Clement |
| author_sort | Liam Z. Yapp |
| collection | DOAJ |
| description | AimsThe aim of this study was to report the meaningful values of the EuroQol five-dimension three-level questionnaire (EQ-5D-3L) and EuroQol visual analogue scale (EQ-VAS) in patients undergoing primary knee arthroplasty (KA).MethodsThis is a retrospective study of patients undergoing primary KA for osteoarthritis in a university teaching hospital (Royal Infirmary of Edinburgh) (1 January 2013 to 31 December 2019). Pre- and postoperative (one-year) data were prospectively collected for 3,181 patients (median age 69.9 years (interquartile range (IQR) 64.2 to 76.1); females, n = 1,745 (54.9%); median BMI 30.1 kg/m2 (IQR 26.6 to 34.2)). The reliability of the EQ-5D-3L was measured using Cronbach’s alpha. Responsiveness was determined by calculating the anchor-based minimal clinically important difference (MCID), the minimal important change (MIC) (cohort and individual), the patient-acceptable symptom state (PASS) predictive of satisfaction, and the minimal detectable change at 90% confidence intervals (MDC-90).ResultsThe EQ-5D-3L demonstrated good internal consistency with an overall Cronbach alpha of 0.75 (preoperative) and 0.88 (postoperative), respectively. The MCID for the Index score was 0.085 (95% confidence interval (CI) 0.042 to 0.127) and EQ-VAS was 6.41 (95% CI 3.497 to 9.323). The MICCOHORT was 0.289 for the EQ-5D and 5.27 for the EQ-VAS. However, the MICINDIVIDUAL for both the EQ-5D-3L Index (0.105) and EQ-VAS (-1) demonstrated poor-to-acceptable reliability. The MDC-90 was 0.023 for the EQ-5D-3L Index and 1.0 for the EQ-VAS. The PASS for the postoperative EQ-5D-3L Index and EQ-VAS scores predictive of patient satisfaction were 0.708 and 77.0, respectively.ConclusionThe meaningful values of the EQ-5D-3L Index and EQ-VAS scores can be used to measure clinically relevant changes in health-related quality of life in patients undergoing primary KA.Cite this article: Bone Joint Res 2022;11(9):619–628. |
| first_indexed | 2024-04-11T11:34:14Z |
| format | Article |
| id | doaj.art-10b5997ae10246ea9bd08e20c6969b5c |
| institution | Directory Open Access Journal |
| issn | 2046-3758 |
| language | English |
| last_indexed | 2024-04-11T11:34:14Z |
| publishDate | 2022-09-01 |
| publisher | The British Editorial Society of Bone & Joint Surgery |
| record_format | Article |
| series | Bone & Joint Research |
| spelling | doaj.art-10b5997ae10246ea9bd08e20c6969b5c2022-12-22T04:26:01ZengThe British Editorial Society of Bone & Joint SurgeryBone & Joint Research2046-37582022-09-0111961962810.1302/2046-3758.119.BJR-2022-0054.R1Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplastyLiam Z. Yapp0Chloe E. H. Scott1Colin R. Howie2Deborah J. MacDonald3A. Hamish R. W. Simpson4Nick D. Clement5Department of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKDepartment of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKDepartment of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKDepartment of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKDepartment of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKDepartment of Orthopaedics, Division of Clinical and Surgical Sciences, University of Edinburgh, Edinburgh, UKAimsThe aim of this study was to report the meaningful values of the EuroQol five-dimension three-level questionnaire (EQ-5D-3L) and EuroQol visual analogue scale (EQ-VAS) in patients undergoing primary knee arthroplasty (KA).MethodsThis is a retrospective study of patients undergoing primary KA for osteoarthritis in a university teaching hospital (Royal Infirmary of Edinburgh) (1 January 2013 to 31 December 2019). Pre- and postoperative (one-year) data were prospectively collected for 3,181 patients (median age 69.9 years (interquartile range (IQR) 64.2 to 76.1); females, n = 1,745 (54.9%); median BMI 30.1 kg/m2 (IQR 26.6 to 34.2)). The reliability of the EQ-5D-3L was measured using Cronbach’s alpha. Responsiveness was determined by calculating the anchor-based minimal clinically important difference (MCID), the minimal important change (MIC) (cohort and individual), the patient-acceptable symptom state (PASS) predictive of satisfaction, and the minimal detectable change at 90% confidence intervals (MDC-90).ResultsThe EQ-5D-3L demonstrated good internal consistency with an overall Cronbach alpha of 0.75 (preoperative) and 0.88 (postoperative), respectively. The MCID for the Index score was 0.085 (95% confidence interval (CI) 0.042 to 0.127) and EQ-VAS was 6.41 (95% CI 3.497 to 9.323). The MICCOHORT was 0.289 for the EQ-5D and 5.27 for the EQ-VAS. However, the MICINDIVIDUAL for both the EQ-5D-3L Index (0.105) and EQ-VAS (-1) demonstrated poor-to-acceptable reliability. The MDC-90 was 0.023 for the EQ-5D-3L Index and 1.0 for the EQ-VAS. The PASS for the postoperative EQ-5D-3L Index and EQ-VAS scores predictive of patient satisfaction were 0.708 and 77.0, respectively.ConclusionThe meaningful values of the EQ-5D-3L Index and EQ-VAS scores can be used to measure clinically relevant changes in health-related quality of life in patients undergoing primary KA.Cite this article: Bone Joint Res 2022;11(9):619–628.https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.119.BJR-2022-0054.R1EQ-5DQuality of lifeKneeOsteoarthritisArthroplastyprimary knee arthroplasty |
| spellingShingle | Liam Z. Yapp Chloe E. H. Scott Colin R. Howie Deborah J. MacDonald A. Hamish R. W. Simpson Nick D. Clement Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty Bone & Joint Research EQ-5D Quality of life Knee Osteoarthritis Arthroplasty primary knee arthroplasty |
| title | Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty |
| title_full | Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty |
| title_fullStr | Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty |
| title_full_unstemmed | Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty |
| title_short | Meaningful values of the EQ-5D-3L in patients undergoing primary knee arthroplasty |
| title_sort | meaningful values of the eq 5d 3l in patients undergoing primary knee arthroplasty |
| topic | EQ-5D Quality of life Knee Osteoarthritis Arthroplasty primary knee arthroplasty |
| url | https://online.boneandjoint.org.uk/doi/10.1302/2046-3758.119.BJR-2022-0054.R1 |
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