Protective effects of fraxin on cerebral ischemia-reperfusion injury by mediating neuroinflammation and oxidative stress through PPAR-γ/NF-κB pathway
Background: Inflammation and oxidative stress are associated with the pathogenesis of cerebral ischemia-reperfusion (I/R) injury. Fraxin, one of the primary active ingredients of Cortex Fraxini, may have potent anti-inflammatory activity. This study intended to investigate the function and mechanism...
Main Authors: | Hongyan Yao, Jianqiang Zhao, XiaoYang Song |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-09-01
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Series: | Brain Research Bulletin |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0361923022001551 |
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