Selection upon genome architecture: conservation of functional neighborhoods with changing genes.
An increasing number of evidences show that genes are not distributed randomly across eukaryotic chromosomes, but rather in functional neighborhoods. Nevertheless, the driving force that originated and maintains such neighborhoods is still a matter of controversy. We present the first detailed multi...
Main Authors: | Fátima Al-Shahrour, Pablo Minguez, Tomás Marqués-Bonet, Elodie Gazave, Arcadi Navarro, Joaquín Dopazo |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
|
Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC2951340?pdf=render |
Similar Items
-
Allele-specific gene expression is widespread across the genome and biological processes.
by: Ricardo Palacios, et al.
Published: (2009-01-01) -
Gene set internal coherence in the context of functional profiling
by: Al-Shahrour Fátima, et al.
Published: (2009-04-01) -
From genes to functional classes in the study of biological systems
by: Huerta-Cepas Jaime, et al.
Published: (2007-04-01) -
Assessing the biological significance of gene expression signatures and co-expression modules by studying their network properties.
by: Pablo Minguez, et al.
Published: (2011-01-01) -
The genomic distribution of intraspecific and interspecific sequence divergence of human segmental duplications relative to human/chimpanzee chromosomal rearrangements
by: Eichler Evan E, et al.
Published: (2008-08-01)