High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules
The dynamics of biomolecules can occur over a wide range of time and length scales. Here the authors develop a high-speed AFM height spectroscopy method to directly detect the motion of unlabeled molecules at Angstrom spatial and microsecond temporal resolution.
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-018-07512-3 |
| _version_ | 1818978644780908544 |
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| author | George R. Heath Simon Scheuring |
| author_facet | George R. Heath Simon Scheuring |
| author_sort | George R. Heath |
| collection | DOAJ |
| description | The dynamics of biomolecules can occur over a wide range of time and length scales. Here the authors develop a high-speed AFM height spectroscopy method to directly detect the motion of unlabeled molecules at Angstrom spatial and microsecond temporal resolution. |
| first_indexed | 2024-12-20T16:46:55Z |
| format | Article |
| id | doaj.art-10b963554d2e41b2b5ae312445bcf43c |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-20T16:46:55Z |
| publishDate | 2018-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-10b963554d2e41b2b5ae312445bcf43c2022-12-21T19:32:55ZengNature PortfolioNature Communications2041-17232018-11-019111110.1038/s41467-018-07512-3High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomoleculesGeorge R. Heath0Simon Scheuring1Weill Cornell Medicine, Department of AnesthesiologyWeill Cornell Medicine, Department of AnesthesiologyThe dynamics of biomolecules can occur over a wide range of time and length scales. Here the authors develop a high-speed AFM height spectroscopy method to directly detect the motion of unlabeled molecules at Angstrom spatial and microsecond temporal resolution.https://doi.org/10.1038/s41467-018-07512-3 |
| spellingShingle | George R. Heath Simon Scheuring High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules Nature Communications |
| title | High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules |
| title_full | High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules |
| title_fullStr | High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules |
| title_full_unstemmed | High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules |
| title_short | High-speed AFM height spectroscopy reveals µs-dynamics of unlabeled biomolecules |
| title_sort | high speed afm height spectroscopy reveals µs dynamics of unlabeled biomolecules |
| url | https://doi.org/10.1038/s41467-018-07512-3 |
| work_keys_str_mv | AT georgerheath highspeedafmheightspectroscopyrevealsμsdynamicsofunlabeledbiomolecules AT simonscheuring highspeedafmheightspectroscopyrevealsμsdynamicsofunlabeledbiomolecules |