Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil
Leprosy and hepatitis B virus (HBV) are highly endemic in some regions of the state of Mato Grosso, in central Brazil. The association of leprosy with HBV and hepatitis C virus (HCV) was assessed using a seroprevalence study and 191 leprosy outpatients were included. Demographic data and the clinica...
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2011-08-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000500019&lng=en&tlng=en |
| _version_ | 1797757089636941824 |
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| author | José María Hernández Ramos Ágabo Macêdo Costa e Silva Regina Maria Bringel Martins Francisco José Dutra Souto |
| author_facet | José María Hernández Ramos Ágabo Macêdo Costa e Silva Regina Maria Bringel Martins Francisco José Dutra Souto |
| author_sort | José María Hernández Ramos |
| collection | DOAJ |
| description | Leprosy and hepatitis B virus (HBV) are highly endemic in some regions of the state of Mato Grosso, in central Brazil. The association of leprosy with HBV and hepatitis C virus (HCV) was assessed using a seroprevalence study and 191 leprosy outpatients were included. Demographic data and the clinical classification of leprosy were recorded. Evidence of previous HBV infection was present in 53 patients (27.7%, 95% confidence interval: 21.9-34.5) and two (1%) were HBsAg positive. Five (2.6%) had antibodies to HCV. The prevalence of previous exposure to HBV was higher than expected for an adult population in central Brazil. In contrast, the prevalence of anti-HCV antibodies was not much higher regarding the age range of participants. HBV markers were associated with a higher number of sex partners and the use of injections without proper sterilisation of the syringes. The number of HBV carriers was small, suggesting that there was no increased likelihood of chronification among these patients. |
| first_indexed | 2024-03-12T18:10:56Z |
| format | Article |
| id | doaj.art-10bb647eae774ea0abc195c5567b3b14 |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T18:10:56Z |
| publishDate | 2011-08-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-10bb647eae774ea0abc195c5567b3b142023-08-02T09:15:28ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602011-08-01106563263410.1590/S0074-02762011000500019S0074-02762011000500019Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central BrazilJosé María Hernández Ramos0Ágabo Macêdo Costa e Silva1Regina Maria Bringel Martins2Francisco José Dutra Souto3Universidade Federal de Mato GrossoUniversidade Federal de GoiásUniversidade Federal de GoiásUniversidade Federal de Mato GrossoLeprosy and hepatitis B virus (HBV) are highly endemic in some regions of the state of Mato Grosso, in central Brazil. The association of leprosy with HBV and hepatitis C virus (HCV) was assessed using a seroprevalence study and 191 leprosy outpatients were included. Demographic data and the clinical classification of leprosy were recorded. Evidence of previous HBV infection was present in 53 patients (27.7%, 95% confidence interval: 21.9-34.5) and two (1%) were HBsAg positive. Five (2.6%) had antibodies to HCV. The prevalence of previous exposure to HBV was higher than expected for an adult population in central Brazil. In contrast, the prevalence of anti-HCV antibodies was not much higher regarding the age range of participants. HBV markers were associated with a higher number of sex partners and the use of injections without proper sterilisation of the syringes. The number of HBV carriers was small, suggesting that there was no increased likelihood of chronification among these patients.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000500019&lng=en&tlng=enleprosyepidemiologyprevalencehepatitis Chepatitis Bviral hepatitis |
| spellingShingle | José María Hernández Ramos Ágabo Macêdo Costa e Silva Regina Maria Bringel Martins Francisco José Dutra Souto Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil Memorias do Instituto Oswaldo Cruz leprosy epidemiology prevalence hepatitis C hepatitis B viral hepatitis |
| title | Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil |
| title_full | Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil |
| title_fullStr | Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil |
| title_full_unstemmed | Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil |
| title_short | Prevalence of hepatitis B and C virus infection among leprosy patients in a leprosy-endemic region of central Brazil |
| title_sort | prevalence of hepatitis b and c virus infection among leprosy patients in a leprosy endemic region of central brazil |
| topic | leprosy epidemiology prevalence hepatitis C hepatitis B viral hepatitis |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000500019&lng=en&tlng=en |
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