Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed CellsSummary

Oxygen and Conformation Dependent Protein Oxidation and Aggregation by Porphyrins in Hepatocytes and Light-Exposed CellsSummary

Background & Aims: Porphyrias are caused by porphyrin accumulation resulting from defects in the heme biosynthetic pathway that typically lead to photosensitivity and possible end-stage liver disease with an increased risk of hepatocellular carcinoma. Our aims were to study the mechanism of porp...

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Bibliographic Details
Main Authors: Dhiman Maitra, Eric L. Carter, Rani Richardson, Laure Rittié, Venkatesha Basrur, Haoming Zhang, Alexey I. Nesvizhskii, Yoichi Osawa, Matthew W. Wolf, Stephen W. Ragsdale, Nicolai Lehnert, Harald Herrmann, M. Bishr Omary
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19300724

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