Protection against Radiotherapy-Induced Toxicity
Radiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60% of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation therapy does, however, cause a wide range of adverse effects that can be severe and cause permanent damage to...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2016-07-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | http://www.mdpi.com/2076-3921/5/3/22 |
| _version_ | 1797707105958887424 |
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| author | Susan Hall Santosh Rudrawar Matthew Zunk Nijole Bernaitis Devinder Arora Catherine M McDermott Shailendra Anoopkumar-Dukie |
| author_facet | Susan Hall Santosh Rudrawar Matthew Zunk Nijole Bernaitis Devinder Arora Catherine M McDermott Shailendra Anoopkumar-Dukie |
| author_sort | Susan Hall |
| collection | DOAJ |
| description | Radiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60% of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation therapy does, however, cause a wide range of adverse effects that can be severe and cause permanent damage to the patient. In an attempt to minimize these effects, a small number of compounds have been identified and are in use clinically for the prevention and treatment of radiation associated toxicities. Furthermore, there are a number of emerging therapies being developed for use as agents that protect against radiation-induced toxicities. The aim of this review was to evaluate and summarise the evidence that exists for both the known radioprotectant agents and the agents that show promise as future radioprotectant agents. |
| first_indexed | 2024-03-12T06:02:29Z |
| format | Article |
| id | doaj.art-10bf9d45f65c4c00bcb0e72a1b45440c |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-12T06:02:29Z |
| publishDate | 2016-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-10bf9d45f65c4c00bcb0e72a1b45440c2023-09-03T03:59:54ZengMDPI AGAntioxidants2076-39212016-07-01532210.3390/antiox5030022antiox5030022Protection against Radiotherapy-Induced ToxicitySusan Hall0Santosh Rudrawar1Matthew Zunk2Nijole Bernaitis3Devinder Arora4Catherine M McDermott5Shailendra Anoopkumar-Dukie6Menzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaCentre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Robina 4226, AustraliaMenzies Health Institute Queensland, Griffith University, Gold Coast 4222, AustraliaRadiation therapy is a highly utilized therapy in the treatment of malignancies with up to 60% of cancer patients receiving radiation therapy as a part of their treatment regimen. Radiation therapy does, however, cause a wide range of adverse effects that can be severe and cause permanent damage to the patient. In an attempt to minimize these effects, a small number of compounds have been identified and are in use clinically for the prevention and treatment of radiation associated toxicities. Furthermore, there are a number of emerging therapies being developed for use as agents that protect against radiation-induced toxicities. The aim of this review was to evaluate and summarise the evidence that exists for both the known radioprotectant agents and the agents that show promise as future radioprotectant agents.http://www.mdpi.com/2076-3921/5/3/22radiotherapytoxicityoxidative stressinflammation |
| spellingShingle | Susan Hall Santosh Rudrawar Matthew Zunk Nijole Bernaitis Devinder Arora Catherine M McDermott Shailendra Anoopkumar-Dukie Protection against Radiotherapy-Induced Toxicity Antioxidants radiotherapy toxicity oxidative stress inflammation |
| title | Protection against Radiotherapy-Induced Toxicity |
| title_full | Protection against Radiotherapy-Induced Toxicity |
| title_fullStr | Protection against Radiotherapy-Induced Toxicity |
| title_full_unstemmed | Protection against Radiotherapy-Induced Toxicity |
| title_short | Protection against Radiotherapy-Induced Toxicity |
| title_sort | protection against radiotherapy induced toxicity |
| topic | radiotherapy toxicity oxidative stress inflammation |
| url | http://www.mdpi.com/2076-3921/5/3/22 |
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