The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study
Background: Poor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients. Objective: This study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enh...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Centro de Investigaciones y Publicaciones Farmaceuticas
2017-09-01
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| Series: | Pharmacy Practice |
| Subjects: | |
| Online Access: | https://www.pharmacypractice.org/journal/index.php/pp/article/view/1026/528 |
| _version_ | 1818283859614105600 |
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| author | Erku DA Ayele AA Mekuria AB Belachew SA Hailemeskel B Tegegn HG |
| author_facet | Erku DA Ayele AA Mekuria AB Belachew SA Hailemeskel B Tegegn HG |
| author_sort | Erku DA |
| collection | DOAJ |
| description | Background: Poor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients.
Objective: This study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enhance medication adherence and reduce hospital admission in patients with type 2 diabetes mellitus.
Methods: A prospective randomized controlled study was conducted in patients with type 2 diabetes mellitus from February 1 to July 30, 2016. Patients in the control group (n=65) received the usual care while patients in the intervention group (n=62) received a personalized pharmacotherapeutic care plan and diabetes education. The two groups were compared by repeated measure ANOVA at 3 and 6‐months with medication adherence (using Morisky medication adherence scale) and number of hospital admissions as the main outcome variables.
Results: A total of 127 patients were included in the study. A marked and statistically significant increase in medication adherence from baseline to 3 and 6 months were noted in the intervention group (increased from 9.2% at baseline to 61% at 6 month) compared with the control group (increased from 13.2% at baseline (to 30.2% at 6 month; p-value<0.01). Furthermore, at the 6-month follow-up, only 23 patients in MTM group with poorly controlled blood glucose levels resulted in hospital admissions compared to 48 patients in non-MTM group, resulting in a 52.1% fewer hospital admissions (p< 0.001).
Conclusions: The findings of this study implied that pharmacist-led medication therapy management might improve medication adherence and reduce number of hospitalizations in patients with type 2 diabetes mellitus. Hence, policies and guidelines should be in place in order for clinical pharmacists to fully engage in patient care and improve the medication therapy outcomes. |
| first_indexed | 2024-12-13T00:43:36Z |
| format | Article |
| id | doaj.art-10c130c38c654b94b38924070d3323f0 |
| institution | Directory Open Access Journal |
| issn | 1885-642X 1886-3655 |
| language | English |
| last_indexed | 2024-12-13T00:43:36Z |
| publishDate | 2017-09-01 |
| publisher | Centro de Investigaciones y Publicaciones Farmaceuticas |
| record_format | Article |
| series | Pharmacy Practice |
| spelling | doaj.art-10c130c38c654b94b38924070d3323f02022-12-22T00:05:05ZengCentro de Investigaciones y Publicaciones FarmaceuticasPharmacy Practice1885-642X1886-36552017-09-011531026102610.18549/PharmPract.2017.03.1026The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled studyErku DAAyele AAMekuria ABBelachew SAHailemeskel BTegegn HGBackground: Poor adherence to antidiabetic medications leads to a higher rate of hospital admissions and adverse health outcomes in type 2 diabetes mellitus patients. Objective: This study aims to evaluate whether a pharmacist-led medication therapy management, compared to the usual care, could enhance medication adherence and reduce hospital admission in patients with type 2 diabetes mellitus. Methods: A prospective randomized controlled study was conducted in patients with type 2 diabetes mellitus from February 1 to July 30, 2016. Patients in the control group (n=65) received the usual care while patients in the intervention group (n=62) received a personalized pharmacotherapeutic care plan and diabetes education. The two groups were compared by repeated measure ANOVA at 3 and 6‐months with medication adherence (using Morisky medication adherence scale) and number of hospital admissions as the main outcome variables. Results: A total of 127 patients were included in the study. A marked and statistically significant increase in medication adherence from baseline to 3 and 6 months were noted in the intervention group (increased from 9.2% at baseline to 61% at 6 month) compared with the control group (increased from 13.2% at baseline (to 30.2% at 6 month; p-value<0.01). Furthermore, at the 6-month follow-up, only 23 patients in MTM group with poorly controlled blood glucose levels resulted in hospital admissions compared to 48 patients in non-MTM group, resulting in a 52.1% fewer hospital admissions (p< 0.001). Conclusions: The findings of this study implied that pharmacist-led medication therapy management might improve medication adherence and reduce number of hospitalizations in patients with type 2 diabetes mellitus. Hence, policies and guidelines should be in place in order for clinical pharmacists to fully engage in patient care and improve the medication therapy outcomes.https://www.pharmacypractice.org/journal/index.php/pp/article/view/1026/528Diabetes Mellitus Type 2Medication Therapy ManagementMedication AdherencePharmacistsTreatment OutcomePatient Education as TopicEthiopia |
| spellingShingle | Erku DA Ayele AA Mekuria AB Belachew SA Hailemeskel B Tegegn HG The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study Pharmacy Practice Diabetes Mellitus Type 2 Medication Therapy Management Medication Adherence Pharmacists Treatment Outcome Patient Education as Topic Ethiopia |
| title | The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study |
| title_full | The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study |
| title_fullStr | The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study |
| title_full_unstemmed | The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study |
| title_short | The impact of pharmacist-led medication therapy management on medication adherence in patients with type 2 diabetes mellitus: a randomized controlled study |
| title_sort | impact of pharmacist led medication therapy management on medication adherence in patients with type 2 diabetes mellitus a randomized controlled study |
| topic | Diabetes Mellitus Type 2 Medication Therapy Management Medication Adherence Pharmacists Treatment Outcome Patient Education as Topic Ethiopia |
| url | https://www.pharmacypractice.org/journal/index.php/pp/article/view/1026/528 |
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