Repeated Cocaine Intake Differentially Impacts Striatal D<sub>2/3</sub> Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse

Repeated Cocaine Intake Differentially Impacts Striatal D<sub>2/3</sub> Receptor Availability, Psychostimulant-Induced Dopamine Release, and Trait Behavioral Markers of Drug Abuse

Current research indicates that altered dopamine (DA) transmission in the striatum contributes to impulsivity and novelty-seeking, and it may mediate a link concerning a higher susceptibility to drug abuse. Whether increased susceptibility to drug abuse results from a hyperdopaminergic or hypodopami...

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Bibliographic Details
Main Authors: Ginna Urueña-Méndez, Andrea Dimiziani, Lidia Bellés, Raphaël Goutaudier, Nathalie Ginovart
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
dopamine
D<sub>2/3</sub> receptors
impulsivity
novelty-seeking
drug abuse
addiction
Online Access:https://www.mdpi.com/1422-0067/24/17/13238

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