RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein

RBM5-AS1 promotes radioresistance in medulloblastoma through stabilization of SIRT6 protein

Abstract Cancer stem cells (CSCs) contribute to radioresistance in medulloblastoma. Thus, identification of key regulators of medulloblastoma stemness is critical for improving radiotherapy for medulloblastoma. In the present study, we profiled CSC-related long non-coding RNAs (lncRNAs) between radi...

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Bibliographic Details
Main Authors: Chuanying Zhu, Keke Li, Mawei Jiang, Siyu Chen
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Acta Neuropathologica Communications
Subjects:
Medulloblastoma
RBM5-AS1
Protein stability
Radioresistance
Stemness
Online Access:https://doi.org/10.1186/s40478-021-01218-2

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