Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms

Snakebite is a neglected tropical disease that causes high rates of global mortality and morbidity. Although snakebite can cause a variety of pathologies in victims, haemotoxic effects are particularly common and are typically characterised by haemorrhage and/or venom-induced consumption coagulopath...

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Bibliographic Details
Main Authors: Nessrin Alomran, Patricia Blundell, Jaffer Alsolaiss, Edouard Crittenden, Stuart Ainsworth, Charlotte A. Dawson, Rebecca J. Edge, Steven R. Hall, Robert A. Harrison, Mark C. Wilkinson, Stefanie K. Menzies, Nicholas R. Casewell
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Toxins
Subjects:
antivenom
immunogen
polyclonal antibodies
recombinant expression
snake venom toxin
serine proteases
Online Access:https://www.mdpi.com/2072-6651/14/7/443

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