High-level artemisinin-resistance with quinine co-resistance emerges in P. falciparum malaria under in vivo artesunate pressure
Abstract Background Humanity has become largely dependent on artemisinin derivatives for both the treatment and control of malaria, with few alternatives available. A Plasmodium falciparum phenotype with delayed parasite clearance during artemisinin-based combination therapy has established in South...
Main Authors: | Rajeev K. Tyagi, Patrick J. Gleeson, Ludovic Arnold, Rachida Tahar, Eric Prieur, Laurent Decosterd, Jean-Louis Pérignon, Piero Olliaro, Pierre Druilhe |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-10-01
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Series: | BMC Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12916-018-1156-x |
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