Novel Naturally Occurring Mutations of Enterovirus 71 Associated With Disease Severity

Novel Naturally Occurring Mutations of Enterovirus 71 Associated With Disease Severity

Infection with the re-emerging enterovirus 71 (EV-A71) is associated with a wide range of disease severity, including herpangina, encephalitis, and cardiopulmonary failure. At present, there is no FDA-approved therapeutics for EV-A71. Early diagnosis for the high-risk children is the key to successf...

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Bibliographic Details
Main Authors: Chih-Shin Chang, Chun-Che Liao, An-Ting Liou, Yi-Chun Chou, Ya-Yen Yu, Chi-Yung Lin, Jen-Shiou Lin, Ching-Shu Suen, Ming-Jing Hwang, Chiaho Shih
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Microbiology
Subjects:
enterovirus 71
EV-A71
disease severity
mutations
VP1
VP2
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2020.610568/full

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