| Summary: | Mechanical parameters of hard and soft tissues are explicit markers for quantitative tissue characterization. In this study, we present a biphasic 3D-FE-based method to determine the biomechanical properties of equine articular cartilage from creep indentation tests (F = 0.1 N, t = 1000 s). The FE-model computation was optimized by exploiting the axial symmetry and mesh resolution. Parameter identification was executed with the Levenberg-Marquardt-algorithm. Additionally, sensitivity analyses of the calculated biomechanical parameters were performed. Results show that the Young’s modulus has the largest influence and the Poisson’s ratio of ν ≤ 0.1 is rather insensitive. The R² of the fit results varies between 0.882 and 0.974. The determined values for the Young’s modulus were 0.806 ± 0.093 MPa, the Poisson’s ratio 0.03 ± 0.06 and the permeability 0.012 ± 0.002 mm4/Ns. Future work will deal with mathematical extensions of the biphasic 3D-FE-model.
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