Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment

The increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology. Pulsed field ablation (PFA), a novel recently developed non-thermal energy-based technique, uses trains...

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Main Authors: Fuding Guo, Jun Wang, Liping Zhou, Yueyi Wang, Hong Jiang, Lilei Yu
Format: Article
Language:English
Published: Compuscript Ltd 2023-03-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0019
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author Fuding Guo
Jun Wang
Liping Zhou
Yueyi Wang
Hong Jiang
Lilei Yu
author_facet Fuding Guo
Jun Wang
Liping Zhou
Yueyi Wang
Hong Jiang
Lilei Yu
author_sort Fuding Guo
collection DOAJ
description The increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology. Pulsed field ablation (PFA), a novel recently developed non-thermal energy-based technique, uses trains of microsecond duration high-amplitude pulses to ablate target cells. Several preclinical and clinical studies have demonstrated that PFA is a promising tool for cardiac ablation to treat arrhythmia. In addition to being an effective tissue ablation technique, PFA is safe, because it avoids damage to the surrounding cells/tissues. This review focuses on efficacy and safety outcomes reported in preclinical and clinical studies evaluating the effects of PFA on arrhythmia, and discusses limitations and potential future directions of PFA.
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spelling doaj.art-10e375e70a7b4b16874e25810dedab832023-11-25T17:00:32ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822023-03-018199810.15212/CVIA.2023.0019Advances in the Application of Pulsed Field Ablation for Arrhythmia TreatmentFuding GuoJun WangLiping ZhouYueyi WangHong JiangLilei YuThe increased application of catheter ablation to treat cardiac arrhythmias has contributed to continued exploration of safe and effective tissue ablation tools in the field of electrophysiology. Pulsed field ablation (PFA), a novel recently developed non-thermal energy-based technique, uses trains of microsecond duration high-amplitude pulses to ablate target cells. Several preclinical and clinical studies have demonstrated that PFA is a promising tool for cardiac ablation to treat arrhythmia. In addition to being an effective tissue ablation technique, PFA is safe, because it avoids damage to the surrounding cells/tissues. This review focuses on efficacy and safety outcomes reported in preclinical and clinical studies evaluating the effects of PFA on arrhythmia, and discusses limitations and potential future directions of PFA.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0019
spellingShingle Fuding Guo
Jun Wang
Liping Zhou
Yueyi Wang
Hong Jiang
Lilei Yu
Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
Cardiovascular Innovations and Applications
title Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
title_full Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
title_fullStr Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
title_full_unstemmed Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
title_short Advances in the Application of Pulsed Field Ablation for Arrhythmia Treatment
title_sort advances in the application of pulsed field ablation for arrhythmia treatment
url https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2023.0019
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AT yueyiwang advancesintheapplicationofpulsedfieldablationforarrhythmiatreatment
AT hongjiang advancesintheapplicationofpulsedfieldablationforarrhythmiatreatment
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