Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion
The formation of Zn(II), Cd(II) and Hg(II) complexes was studied with two new hetrocyclic azo ligands 2-[4-(1-sulfonaphthalene)azo]-L-Histidine (L1) and 2-[7-(1-hydroxy3-sulfonaphthalene)azo]-L-Histidine (L2) derived from coupling reaction of diazonium salt of naphthionic acid and 7-amino-1-naphtho...
| Main Author: | |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
University of Baghdad
2017-03-01
|
| Series: | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| Subjects: | |
| Online Access: | https://jih.uobaghdad.edu.iq/index.php/j/article/view/151 |
| _version_ | 1817985057774632960 |
|---|---|
| author | Alyaa K. Abass |
| author_facet | Alyaa K. Abass |
| author_sort | Alyaa K. Abass |
| collection | DOAJ |
| description |
The formation of Zn(II), Cd(II) and Hg(II) complexes was studied with two new hetrocyclic azo ligands 2-[4-(1-sulfonaphthalene)azo]-L-Histidine (L1) and 2-[7-(1-hydroxy3-sulfonaphthalene)azo]-L-Histidine (L2) derived from coupling reaction of diazonium salt of naphthionic acid and 7-amino-1-naphthol-5-sulfonic acid with L-Histidine in an alkaline ethanolic solution. The structural features of all new compounds have been characterized from their elemental analyses, metal content, magnetic moment measurement, molar conductance & FT-IR, UV-Vis. and 1HNMR spectral studies. Furthermore,the composition of complexes have been studied following the mole ratio method after fixing the optimum condition (pH and concentration).Beer’s law was obeyed over a concentration range (6ï‚´10-5 - 8ï‚´10-5M). All data showed that the complexes with (1:2) (M:L) metal to ligand, may be formulated as [M(L)2Cl2] and octahedral geometry, in which the ligands (L1 and L2) act as N,N-bidentate chelating agents, coordinated through the azo nitrogen near naphthyl moiety and heterocyclic nitrogen in L-Histidine. The stability constant (ï¢) and Gibbs free energy (ï„G) of the complexes have also been studied. Biological efficiency of ligands and their complexes were tested aginst Eschericha coli and Staphylococcus aureus.
|
| first_indexed | 2024-04-13T23:53:20Z |
| format | Article |
| id | doaj.art-10e3f8abf5cf443199778975cca783b2 |
| institution | Directory Open Access Journal |
| issn | 1609-4042 2521-3407 |
| language | English |
| last_indexed | 2024-04-13T23:53:20Z |
| publishDate | 2017-03-01 |
| publisher | University of Baghdad |
| record_format | Article |
| series | Ibn Al-Haitham Journal for Pure and Applied Sciences |
| spelling | doaj.art-10e3f8abf5cf443199778975cca783b22022-12-22T02:24:00ZengUniversity of BaghdadIbn Al-Haitham Journal for Pure and Applied Sciences1609-40422521-34072017-03-01283Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ionAlyaa K. Abass The formation of Zn(II), Cd(II) and Hg(II) complexes was studied with two new hetrocyclic azo ligands 2-[4-(1-sulfonaphthalene)azo]-L-Histidine (L1) and 2-[7-(1-hydroxy3-sulfonaphthalene)azo]-L-Histidine (L2) derived from coupling reaction of diazonium salt of naphthionic acid and 7-amino-1-naphthol-5-sulfonic acid with L-Histidine in an alkaline ethanolic solution. The structural features of all new compounds have been characterized from their elemental analyses, metal content, magnetic moment measurement, molar conductance & FT-IR, UV-Vis. and 1HNMR spectral studies. Furthermore,the composition of complexes have been studied following the mole ratio method after fixing the optimum condition (pH and concentration).Beer’s law was obeyed over a concentration range (6ï‚´10-5 - 8ï‚´10-5M). All data showed that the complexes with (1:2) (M:L) metal to ligand, may be formulated as [M(L)2Cl2] and octahedral geometry, in which the ligands (L1 and L2) act as N,N-bidentate chelating agents, coordinated through the azo nitrogen near naphthyl moiety and heterocyclic nitrogen in L-Histidine. The stability constant (ï¢) and Gibbs free energy (ï„G) of the complexes have also been studied. Biological efficiency of ligands and their complexes were tested aginst Eschericha coli and Staphylococcus aureus. https://jih.uobaghdad.edu.iq/index.php/j/article/view/151L-Histidine, Azo lignads, structural studies, biological efficiency. |
| spellingShingle | Alyaa K. Abass Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion Ibn Al-Haitham Journal for Pure and Applied Sciences L-Histidine, Azo lignads, structural studies, biological efficiency. |
| title | Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion |
| title_full | Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion |
| title_fullStr | Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion |
| title_full_unstemmed | Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion |
| title_short | Synthesis, Structural and Biological Efficiency Studies of New Azo Ligands and Their complxes with Zn(II), Cd(II) and Hg(II) Metal ion |
| title_sort | synthesis structural and biological efficiency studies of new azo ligands and their complxes with zn ii cd ii and hg ii metal ion |
| topic | L-Histidine, Azo lignads, structural studies, biological efficiency. |
| url | https://jih.uobaghdad.edu.iq/index.php/j/article/view/151 |
| work_keys_str_mv | AT alyaakabass synthesisstructuralandbiologicalefficiencystudiesofnewazoligandsandtheircomplxeswithzniicdiiandhgiimetalion |