SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME

The current clinical guidelines for the treatment of patients with acute coronary syndrome (ACS) claim that simultaneous use of two drugs that inhibit platelet activity is mandatory for most patients. This approach known as dual antiplatelet therapy (DAT), in view of the similarity of the mechanisms...

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Main Author: A. D. Erlikh
Format: Article
Language:Russian
Published: «REMEDIUM GROUP» Ltd. 2017-05-01
Series:Атеротромбоз
Subjects:
Online Access:https://www.aterotromboz.ru/jour/article/view/108
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author A. D. Erlikh
author_facet A. D. Erlikh
author_sort A. D. Erlikh
collection DOAJ
description The current clinical guidelines for the treatment of patients with acute coronary syndrome (ACS) claim that simultaneous use of two drugs that inhibit platelet activity is mandatory for most patients. This approach known as dual antiplatelet therapy (DAT), in view of the similarity of the mechanisms of the disease development, should be used in both ACS with ST elevation (STE-ACS) and in ACS without ST elevation (non-STE-ACS). In both cases, DAT should combine acetylsalicylic acid (ASA) with a P2Y12 receptor antagonist (ticagrelor, prasugrel or clopidogrel). For Russia, where prasugrel is not registered, the most preferable DAT is the combination of ASA with ticagrelor which has outperformed clopidogrel in terms of efficacy in the PLATO trial. [1]
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spelling doaj.art-10e625d1e03146cb817393894c2249e82025-03-02T09:27:28Zrus«REMEDIUM GROUP» Ltd.Атеротромбоз2307-11092658-59522017-05-0101445210.21518/2307-1109-2017-1-44-52102SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROMEA. D. Erlikh0City Clinical Hospital No. 29 named after N.E. BaumanThe current clinical guidelines for the treatment of patients with acute coronary syndrome (ACS) claim that simultaneous use of two drugs that inhibit platelet activity is mandatory for most patients. This approach known as dual antiplatelet therapy (DAT), in view of the similarity of the mechanisms of the disease development, should be used in both ACS with ST elevation (STE-ACS) and in ACS without ST elevation (non-STE-ACS). In both cases, DAT should combine acetylsalicylic acid (ASA) with a P2Y12 receptor antagonist (ticagrelor, prasugrel or clopidogrel). For Russia, where prasugrel is not registered, the most preferable DAT is the combination of ASA with ticagrelor which has outperformed clopidogrel in terms of efficacy in the PLATO trial. [1]https://www.aterotromboz.ru/jour/article/view/108acute coronary syndromedual antiplatelet therapyacetylsalicylic acidticagrelor
spellingShingle A. D. Erlikh
SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
Атеротромбоз
acute coronary syndrome
dual antiplatelet therapy
acetylsalicylic acid
ticagrelor
title SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
title_full SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
title_fullStr SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
title_full_unstemmed SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
title_short SOME ASPECTS OF IMPROVING ADHERENCE TO DUAL ANTITHROMBOTIC THERAPY AFTER ACUTE CORONARY SYNDROME
title_sort some aspects of improving adherence to dual antithrombotic therapy after acute coronary syndrome
topic acute coronary syndrome
dual antiplatelet therapy
acetylsalicylic acid
ticagrelor
url https://www.aterotromboz.ru/jour/article/view/108
work_keys_str_mv AT aderlikh someaspectsofimprovingadherencetodualantithrombotictherapyafteracutecoronarysyndrome