Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis
Biomass-derived C6-furanic compounds have become the cornerstone of sustainable technologies. The key feature of this field of chemistry is the involvement of the natural process only in the first step, i.e., the production of biomass by photosynthesis. Biomass-to-HMF (5-hydroxymethylfurfural) conve...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-02-01
|
| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/4/3997 |
| _version_ | 1797620381004070912 |
|---|---|
| author | Leonid V. Romashov Fedor A. Kucherov Kirill S. Kozlov Valentine P. Ananikov |
| author_facet | Leonid V. Romashov Fedor A. Kucherov Kirill S. Kozlov Valentine P. Ananikov |
| author_sort | Leonid V. Romashov |
| collection | DOAJ |
| description | Biomass-derived C6-furanic compounds have become the cornerstone of sustainable technologies. The key feature of this field of chemistry is the involvement of the natural process only in the first step, i.e., the production of biomass by photosynthesis. Biomass-to-HMF (5-hydroxymethylfurfural) conversion and further transformations are carried out externally with the involvement of processes with poor environmental factors (E-factors) and the generation of chemical wastes. Due to widespread interest, the chemical conversion of biomass to furanic platform chemicals and related transformations are thoroughly studied and well-reviewed in the current literature. In contrast, a novel opportunity is based on an alternative approach to consider the synthesis of C6-furanics inside living cells using natural metabolism, as well as further transformations to a variety of functionalized products. In the present article, we review naturally occurring substances containing C6-furanic cores and focus on the diversity of C6-furanic derivatives, occurrence, properties and synthesis. From the practical point of view, organic synthesis involving natural metabolism is advantageous in terms of sustainability (sunlight-driven as the only energy source) and green nature (no eco-persisted chemical wastes). |
| first_indexed | 2024-03-11T08:40:24Z |
| format | Article |
| id | doaj.art-10e99fc20bf945b690247a5b884976b7 |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T08:40:24Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-10e99fc20bf945b690247a5b884976b72023-11-16T21:08:19ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-02-01244399710.3390/ijms24043997Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic SynthesisLeonid V. Romashov0Fedor A. Kucherov1Kirill S. Kozlov2Valentine P. Ananikov3N.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, RussiaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, RussiaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, RussiaN.D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Leninsky Prospect 47, Moscow 119991, RussiaBiomass-derived C6-furanic compounds have become the cornerstone of sustainable technologies. The key feature of this field of chemistry is the involvement of the natural process only in the first step, i.e., the production of biomass by photosynthesis. Biomass-to-HMF (5-hydroxymethylfurfural) conversion and further transformations are carried out externally with the involvement of processes with poor environmental factors (E-factors) and the generation of chemical wastes. Due to widespread interest, the chemical conversion of biomass to furanic platform chemicals and related transformations are thoroughly studied and well-reviewed in the current literature. In contrast, a novel opportunity is based on an alternative approach to consider the synthesis of C6-furanics inside living cells using natural metabolism, as well as further transformations to a variety of functionalized products. In the present article, we review naturally occurring substances containing C6-furanic cores and focus on the diversity of C6-furanic derivatives, occurrence, properties and synthesis. From the practical point of view, organic synthesis involving natural metabolism is advantageous in terms of sustainability (sunlight-driven as the only energy source) and green nature (no eco-persisted chemical wastes).https://www.mdpi.com/1422-0067/24/4/3997biomassbioderived chemicalsorganic synthesisfuranHMFnatural products |
| spellingShingle | Leonid V. Romashov Fedor A. Kucherov Kirill S. Kozlov Valentine P. Ananikov Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis International Journal of Molecular Sciences biomass bioderived chemicals organic synthesis furan HMF natural products |
| title | Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis |
| title_full | Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis |
| title_fullStr | Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis |
| title_full_unstemmed | Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis |
| title_short | Bio-Derived Furanic Compounds with Natural Metabolism: New Sustainable Possibilities for Selective Organic Synthesis |
| title_sort | bio derived furanic compounds with natural metabolism new sustainable possibilities for selective organic synthesis |
| topic | biomass bioderived chemicals organic synthesis furan HMF natural products |
| url | https://www.mdpi.com/1422-0067/24/4/3997 |
| work_keys_str_mv | AT leonidvromashov bioderivedfuraniccompoundswithnaturalmetabolismnewsustainablepossibilitiesforselectiveorganicsynthesis AT fedorakucherov bioderivedfuraniccompoundswithnaturalmetabolismnewsustainablepossibilitiesforselectiveorganicsynthesis AT kirillskozlov bioderivedfuraniccompoundswithnaturalmetabolismnewsustainablepossibilitiesforselectiveorganicsynthesis AT valentinepananikov bioderivedfuraniccompoundswithnaturalmetabolismnewsustainablepossibilitiesforselectiveorganicsynthesis |