Technical Aspects of in vivo Small Animal CMR Imaging
Cardiovascular magnetic resonance (CMR) imaging has become an accurate and versatile imaging modality to visualize the cardiovascular system in normal or abnormal conditions. In preclinical research, small rodent animal models of human cardiovascular diseases are frequently used to investigate the b...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-06-01
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| Series: | Frontiers in Physics |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fphy.2020.00183/full |
| _version_ | 1818854805299265536 |
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| author | Hao Li Hao Li Alireza Abaei Patrick Metze Steffen Just Qinghua Lu Volker Rasche Volker Rasche |
| author_facet | Hao Li Hao Li Alireza Abaei Patrick Metze Steffen Just Qinghua Lu Volker Rasche Volker Rasche |
| author_sort | Hao Li |
| collection | DOAJ |
| description | Cardiovascular magnetic resonance (CMR) imaging has become an accurate and versatile imaging modality to visualize the cardiovascular system in normal or abnormal conditions. In preclinical research, small rodent animal models of human cardiovascular diseases are frequently used to investigate the basic underlying mechanism of normal and abnormal cardiac function and for monitoring the disease progression under therapy. Technical improvements have enabled the transfer of CMR to small animal research, and as such made this non-invasive technique available to provide insights into cardiac morphology, function, perfusion, and pathophysiology in small animal cardiac disease models. This article reviews the basic technical approaches to in vivo small animal magnetic resonance imaging and its variants for the most promising applications. |
| first_indexed | 2024-12-19T07:58:33Z |
| format | Article |
| id | doaj.art-10ea17dcd3b5463d8f55662f4d6c8c0d |
| institution | Directory Open Access Journal |
| issn | 2296-424X |
| language | English |
| last_indexed | 2024-12-19T07:58:33Z |
| publishDate | 2020-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physics |
| spelling | doaj.art-10ea17dcd3b5463d8f55662f4d6c8c0d2022-12-21T20:29:56ZengFrontiers Media S.A.Frontiers in Physics2296-424X2020-06-01810.3389/fphy.2020.00183520146Technical Aspects of in vivo Small Animal CMR ImagingHao Li0Hao Li1Alireza Abaei2Patrick Metze3Steffen Just4Qinghua Lu5Volker Rasche6Volker Rasche7Ulm University, Core Facility Small Animal Imaging, Ulm, GermanyDepartment of Cardiology, The Second Hospital of Shandong University, Jinan, ChinaUlm University, Core Facility Small Animal Imaging, Ulm, GermanyDepartment of Internal Medicine II, Ulm University Medical Center, Ulm, GermanyDepartment of Internal Medicine II, Ulm University Medical Center, Ulm, GermanyDepartment of Cardiology, The Second Hospital of Shandong University, Jinan, ChinaUlm University, Core Facility Small Animal Imaging, Ulm, GermanyDepartment of Internal Medicine II, Ulm University Medical Center, Ulm, GermanyCardiovascular magnetic resonance (CMR) imaging has become an accurate and versatile imaging modality to visualize the cardiovascular system in normal or abnormal conditions. In preclinical research, small rodent animal models of human cardiovascular diseases are frequently used to investigate the basic underlying mechanism of normal and abnormal cardiac function and for monitoring the disease progression under therapy. Technical improvements have enabled the transfer of CMR to small animal research, and as such made this non-invasive technique available to provide insights into cardiac morphology, function, perfusion, and pathophysiology in small animal cardiac disease models. This article reviews the basic technical approaches to in vivo small animal magnetic resonance imaging and its variants for the most promising applications.https://www.frontiersin.org/article/10.3389/fphy.2020.00183/fullcardiac MRIcardiac MRSimaging techniquessmall animalscardiovascular diseasescardiac function |
| spellingShingle | Hao Li Hao Li Alireza Abaei Patrick Metze Steffen Just Qinghua Lu Volker Rasche Volker Rasche Technical Aspects of in vivo Small Animal CMR Imaging Frontiers in Physics cardiac MRI cardiac MRS imaging techniques small animals cardiovascular diseases cardiac function |
| title | Technical Aspects of in vivo Small Animal CMR Imaging |
| title_full | Technical Aspects of in vivo Small Animal CMR Imaging |
| title_fullStr | Technical Aspects of in vivo Small Animal CMR Imaging |
| title_full_unstemmed | Technical Aspects of in vivo Small Animal CMR Imaging |
| title_short | Technical Aspects of in vivo Small Animal CMR Imaging |
| title_sort | technical aspects of in vivo small animal cmr imaging |
| topic | cardiac MRI cardiac MRS imaging techniques small animals cardiovascular diseases cardiac function |
| url | https://www.frontiersin.org/article/10.3389/fphy.2020.00183/full |
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