Applications of calixarenes in cancer chemotherapy: facts and perspectives

Applications of calixarenes in cancer chemotherapy: facts and perspectives

Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest....

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Bibliographic Details
Main Authors: Yousaf A, Abd Hamid S, Bunnori NM, Ishola AA
Format: Article
Language:English
Published: Dove Medical Press 2015-06-01
Series:Drug Design, Development and Therapy
Online Access:http://www.dovepress.com/applications-of-calixarenes-in-cancer-chemotherapy-facts-and-perspecti-peer-reviewed-article-DDDT
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Summary:Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief. Keywords: cancer, chemotherapy, calixarenes
ISSN:1177-8881

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