Applications of calixarenes in cancer chemotherapy: facts and perspectives
Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2015-06-01
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| Series: | Drug Design, Development and Therapy |
| Online Access: | http://www.dovepress.com/applications-of-calixarenes-in-cancer-chemotherapy-facts-and-perspecti-peer-reviewed-article-DDDT |
| _version_ | 1811344729966641152 |
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| author | Yousaf A Abd Hamid S Bunnori NM Ishola AA |
| author_facet | Yousaf A Abd Hamid S Bunnori NM Ishola AA |
| author_sort | Yousaf A |
| collection | DOAJ |
| description | Ali Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief. Keywords: cancer, chemotherapy, calixarenes |
| first_indexed | 2024-04-13T19:51:34Z |
| format | Article |
| id | doaj.art-10ea95bb470a4075af34b8403db7b58d |
| institution | Directory Open Access Journal |
| issn | 1177-8881 |
| language | English |
| last_indexed | 2024-04-13T19:51:34Z |
| publishDate | 2015-06-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Drug Design, Development and Therapy |
| spelling | doaj.art-10ea95bb470a4075af34b8403db7b58d2022-12-22T02:32:29ZengDove Medical PressDrug Design, Development and Therapy1177-88812015-06-012015default2831283821975Applications of calixarenes in cancer chemotherapy: facts and perspectivesYousaf AAbd Hamid SBunnori NMIshola AAAli Yousaf,1 Shafida Abd Hamid,1 Noraslinda M Bunnori,1 AA Ishola2 1Kulliyyah of Science, 2Kulliyyah of Medicine, International Islamic University Malaysia, Bandar Indera Mahkota, Malaysia Abstract: Research on the therapeutic applications of calixarene derivatives is an emerging area of interest. The anticancer activity of various functionalized calixarenes has been reported by several research groups. Due to their superior geometric shape, calixarenes can accommodate drug molecules by forming inclusion complexes. Controlled release of anticancer drugs by calixarenes might help in targeted chemotherapy. This review summarizes the anticancer potential of the calixarenes and their drug loading properties. The potential use of calixarenes in chemoradiotherapy is also highlighted in brief. Keywords: cancer, chemotherapy, calixareneshttp://www.dovepress.com/applications-of-calixarenes-in-cancer-chemotherapy-facts-and-perspecti-peer-reviewed-article-DDDT |
| spellingShingle | Yousaf A Abd Hamid S Bunnori NM Ishola AA Applications of calixarenes in cancer chemotherapy: facts and perspectives Drug Design, Development and Therapy |
| title | Applications of calixarenes in cancer chemotherapy: facts and perspectives |
| title_full | Applications of calixarenes in cancer chemotherapy: facts and perspectives |
| title_fullStr | Applications of calixarenes in cancer chemotherapy: facts and perspectives |
| title_full_unstemmed | Applications of calixarenes in cancer chemotherapy: facts and perspectives |
| title_short | Applications of calixarenes in cancer chemotherapy: facts and perspectives |
| title_sort | applications of calixarenes in cancer chemotherapy facts and perspectives |
| url | http://www.dovepress.com/applications-of-calixarenes-in-cancer-chemotherapy-facts-and-perspecti-peer-reviewed-article-DDDT |
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