Identification of a DNA Damage Response and Repair-Related Gene-Pair Signature for Prognosis Stratification Analysis in Hepatocellular Carcinoma

Identification of a DNA Damage Response and Repair-Related Gene-Pair Signature for Prognosis Stratification Analysis in Hepatocellular Carcinoma

Background: Nowadays, although the cause of hepatocellular carcinoma (HCC) mortality and recurrence remains at a high level, the 5-year survival rate is still very low. The DNA damage response and repair (DDR) pathway may affect HCC patients’ survival by influencing tumor development and therapeutic...

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Bibliographic Details
Main Authors: Yi Chen, Mengjia Huang, Junkai Zhu, Li Xu, Wenxuan Cheng, Xiaofan Lu, Fangrong Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Pharmacology
Subjects:
DNA damage response and repair
hepatocellular carcinoma
prognosis
HBV
chemotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.857060/full

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