A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions
Abstract Background: Direct transmission of avian influenza viruses with human receptor binding specificity to humans is a serious risk of newly emerging virus responsible for pandemy. The analysis of recent avian influenza hemagglutinin sequences and their glycans show their affinities to the huma...
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| Format: | Article |
| Language: | fas |
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Arak Medical University
2015-08-01
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| Series: | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk |
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| Online Access: | http://amuj.arakmu.ac.ir/article-1-3460-en.pdf |
| _version_ | 1828421827031990272 |
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| author | Shahla Shahsavandi |
| author_facet | Shahla Shahsavandi |
| author_sort | Shahla Shahsavandi |
| collection | DOAJ |
| description | Abstract
Background: Direct transmission of avian influenza viruses with human receptor binding specificity to humans is a serious risk of newly emerging virus responsible for pandemy. The analysis of recent avian influenza hemagglutinin sequences and their glycans show their affinities to the human sialic acid receptors. The upregulation of proinflammatory cytokines and type I IFN genes, and host cell death responses contribute to the pathogenesis of influenza infection. Understanding the host cell-virus interactions and replication dynamic of the viruses in different cells is an essential step in surveillance and controlling programs against influenza. |
| first_indexed | 2024-12-10T15:38:36Z |
| format | Article |
| id | doaj.art-10ec1c1c60e54165aff300351a5f5b1b |
| institution | Directory Open Access Journal |
| issn | 1735-5338 2008-644X |
| language | fas |
| last_indexed | 2024-12-10T15:38:36Z |
| publishDate | 2015-08-01 |
| publisher | Arak Medical University |
| record_format | Article |
| series | Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk |
| spelling | doaj.art-10ec1c1c60e54165aff300351a5f5b1b2022-12-22T01:43:10ZfasArak Medical UniversityMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk1735-53382008-644X2015-08-0120185120A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus InteractionsShahla Shahsavandi0Razi Vaccine and Serum Research Institute, Karaj, Iran.Abstract Background: Direct transmission of avian influenza viruses with human receptor binding specificity to humans is a serious risk of newly emerging virus responsible for pandemy. The analysis of recent avian influenza hemagglutinin sequences and their glycans show their affinities to the human sialic acid receptors. The upregulation of proinflammatory cytokines and type I IFN genes, and host cell death responses contribute to the pathogenesis of influenza infection. Understanding the host cell-virus interactions and replication dynamic of the viruses in different cells is an essential step in surveillance and controlling programs against influenza.http://amuj.arakmu.ac.ir/article-1-3460-en.pdfInfluenza viruseHost cell-virus interactionReplication dynamic |
| spellingShingle | Shahla Shahsavandi A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk Influenza viruse Host cell-virus interaction Replication dynamic |
| title | A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions |
| title_full | A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions |
| title_fullStr | A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions |
| title_full_unstemmed | A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions |
| title_short | A Review: Evaluating the Dynamics of Influenza Viruses Replication and Host Cell- Virus Interactions |
| title_sort | review evaluating the dynamics of influenza viruses replication and host cell virus interactions |
| topic | Influenza viruse Host cell-virus interaction Replication dynamic |
| url | http://amuj.arakmu.ac.ir/article-1-3460-en.pdf |
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