Development and Optimization of Luliconazole Spanlastics to Augment the Antifungal Activity against <i>Candida albicans</i>

Development and Optimization of Luliconazole Spanlastics to Augment the Antifungal Activity against <i>Candida albicans</i>

Luliconazole is a new topical imidazole antifungal drug for the treatment of skin infections. It has low solubility and poor skin penetration which limits its therapeutic applications. In order to improve its therapeutic efficacy, spanlastics nanoformulation was developed and optimized using a combi...

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Bibliographic Details
Main Authors: Nabil A. Alhakamy, Mohammed W. Al-Rabia, Shadab Md, Alaa Sirwi, Selwan Saud Khayat, Sahar Saad AlOtaibi, Raghad Abkar Hakami, Hadeel Al Sadoun, Basmah Medhat Eldakhakhny, Wesam H. Abdulaal, Hibah M. Aldawsari, Shaimaa M. Badr-Eldin, Mahmoud A. Elfaky
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Pharmaceutics
Subjects:
luliconazole
spanlastics
particle size
<i>Candida albicans</i> infections
lesion score
Online Access:https://www.mdpi.com/1999-4923/13/7/977

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