Fixed Drug Eruption due to Achiote Dye
Fixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Karger Publishers
2016-01-01
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| Series: | Case Reports in Dermatology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/443949 |
| _version_ | 1819262326834987008 |
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| author | Ian Tattersall Bobby Y. Reddy |
| author_facet | Ian Tattersall Bobby Y. Reddy |
| author_sort | Ian Tattersall |
| collection | DOAJ |
| description | Fixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing. |
| first_indexed | 2024-12-23T19:55:55Z |
| format | Article |
| id | doaj.art-10f073a585bf4b1cafca1c2382e62420 |
| institution | Directory Open Access Journal |
| issn | 1662-6567 |
| language | English |
| last_indexed | 2024-12-23T19:55:55Z |
| publishDate | 2016-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Dermatology |
| spelling | doaj.art-10f073a585bf4b1cafca1c2382e624202022-12-21T17:33:14ZengKarger PublishersCase Reports in Dermatology1662-65672016-01-0181141810.1159/000443949443949Fixed Drug Eruption due to Achiote DyeIan TattersallBobby Y. ReddyFixed drug eruption (FDE) is a localized type IV sensitivity reaction to a systemically introduced allergen. It usually occurs as a result of new medication, making identification and avoidance of the trigger medication straightforward; however, in a rare subset of cases no pharmacological source is identified. In such cases, the causative agent is often a food or food additive. In this report we describe a case of a FDE in a 12-year-old girl recently immigrated to the United States from Ecuador who had no medication exposure over the course of her illness. Through an exhaustive patient history and literature review, we were able to hypothesize that her presentation was caused by a dietary change of the natural achiote dye used in the preparation of yellow rice to a locally available commercial dye mix containing tartrazine, or Yellow 5, which has previously been implicated in both systemic hypersensitivity reactions and specifically in FDE. This report adds to the small body of available literature on non-pharmacological fixed hypersensitivity eruptions and illustrates an effective approach to the management of such a presentation when history is not immediately revealing.http://www.karger.com/Article/FullText/443949TartrazineFixed drug eruptionAchioteFood coloringFood dye |
| spellingShingle | Ian Tattersall Bobby Y. Reddy Fixed Drug Eruption due to Achiote Dye Case Reports in Dermatology Tartrazine Fixed drug eruption Achiote Food coloring Food dye |
| title | Fixed Drug Eruption due to Achiote Dye |
| title_full | Fixed Drug Eruption due to Achiote Dye |
| title_fullStr | Fixed Drug Eruption due to Achiote Dye |
| title_full_unstemmed | Fixed Drug Eruption due to Achiote Dye |
| title_short | Fixed Drug Eruption due to Achiote Dye |
| title_sort | fixed drug eruption due to achiote dye |
| topic | Tartrazine Fixed drug eruption Achiote Food coloring Food dye |
| url | http://www.karger.com/Article/FullText/443949 |
| work_keys_str_mv | AT iantattersall fixeddrugeruptionduetoachiotedye AT bobbyyreddy fixeddrugeruptionduetoachiotedye |